Innate immunity and the role of epithelial barrier during Aspergillus fumigatus infection

E Svirshchevskaya, D Zubkov… - Current immunology …, 2012 - ingentaconnect.com
Fungi are the most important eukaryotic infective agents in Europe which largely overpass
parasite infections. Total number of people dying of fungal infection is increasing and this …

Identification of genes of Aspergillus fumigatus up-regulated during growth on endothelial cells

JC Rhodes, BG Oliver, DS Askew… - Medical …, 2001 - academic.oup.com
Aspergillus fumigatus is an important opportunistic fungal pathogen that can cause acute
invasive disease in neutropenic hosts. Invasive aspergillosis is being diagnosed with …

[HTML][HTML] Interactions of Aspergillus fumigatus conidia with airway epithelial cells: a critical review

CA Croft, L Culibrk, MM Moore, SJ Tebbutt - Frontiers in microbiology, 2016 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that also acts as an
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …

Novel host pathways govern epithelial cell invasion of Aspergillus fumigatus

H Liu, AC Shetty, AS Ibrahim, SG Filler… - Microbiology …, 2023 - Am Soc Microbiol
Invasive aspergillosis is initiated when Aspergillus fumigatus adheres to and invades the
pulmonary epithelial cells that line the airways and alveoli. To gain deeper insight into how …

Regional cytokine responses to pulmonary aspergillosis in immunocompetent rats

AAM El-Muzghi, I Mirkov, J Djokic, AP Aleksandrov… - Immunobiology, 2013 - Elsevier
Rat models of pulmonary aspergillosis are used widely in diagnostic studies and in
exploring antifungal therapeutic modalities, but there is lack of data concerning antifungal …

967. Inhibition of host neuraminidase increases susceptibility to invasive pulmonary aspergillosis

F Van De Veerdonk Jr, I Dewi, C Cunha… - Open Forum …, 2018 - ncbi.nlm.nih.gov
Background Influenza-associated aspergillosis (IAA) is an emerging fungal infection with
high mortality and morbidity and the pathogenesis of this disease is not well understood …

Phagocytosis of Aspergillus fumigatus conidia by primary nasal epithelial cells in vitro

F Botterel, K Gross, O Ibrahim-Granet, K Khoufache… - BMC microbiology, 2008 - Springer
Background Invasive aspergillosis, which is mainly caused by the fungus Aspergillus
fumigatus, is an increasing problem in immunocompromised patients. Infection occurs by …

Aspergillus fumigatus and Aspergillosis

JP Latgé - Clinical microbiology reviews, 1999 - Am Soc Microbiol
Aspergillus fumigatus is one of the most ubiquitous of the airborne saprophytic fungi.
Humans and animals constantly inhale numerous conidia of this fungus. The conidia are …

Immune responses to Aspergillus antigen in IL‐4‐/‐ mice and the effect of eosinophil ablation

VP Kurup, PS Murali, JQ Xia, JN Fink, HY Choi… - Allergy, 1999 - Wiley Online Library
Background: Exposure to Aspergillus fumigatus allergens results in enhanced total serum
IgE and peripheral blood eosinophils in mice. The associated pulmonary inflammation and …

The Role of Interleukin-1 Family Members in the Host Defence Against Aspergillus fumigatus

MS Gresnigt, FL van de Veerdonk - Mycopathologia, 2014 - Springer
Abstract The interleukin (IL)-1 family consists of 11 members, which all play significant roles
in regulating inflammatory responses in the host. IL-1α and IL-1β exert potent pro …