The mRNA expression of prostaglandin E receptors EP2 and EP4 and the changes in glycosaminoglycans in the sheep cervix during the estrous cycle

CM Kershaw-Young, M Khalid, MR McGowan… - Theriogenology, 2009 - Elsevier
Transcervical artificial insemination in sheep is limited by the inability to completely
penetrate the cervix with an inseminating pipette. Penetration is partially enhanced at estrus …

The expression of prostaglandin endoperoxide synthase 2 messenger RNA and the proportion of smooth muscle and collagen in the sheep cervix during the estrous …

CM Kershaw, RJ Scaramuzzi… - Biology of …, 2007 - academic.oup.com
The use of transcervical artificial insemination in sheep is limited because of the anatomy of
the cervix, which restricts the passage of an inseminating pipette into the uterine lumen …

Localization and steroid regulation of prostaglandin E2 receptor protein expression in ovine cervix

T Schmitz, BA Levine, PW Nathanielsz - Reproduction, 2006 - rep.bioscientifica.com
Although prostaglandin E 2 (PGE 2) has been identified as a central mediator of the cervical
ripening process, the mechanisms responsible for PGE 2 ripening are still poorly …

The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe

CM Kershaw-Young, RJ Scaramuzzi, MR McGowan… - Theriogenology, 2010 - Elsevier
There is a degree of cervical relaxation in the ewe at estrus that is regulated by changes in
prostaglandin synthesis, prostaglandin receptor expression, and changes in the cervical …

Regulation of the prostaglandin enzymatic system by estradiol and progesterone in nonpregnant sheep cervix

Q Zhang, V Collins, K Chakrabarty, JC Rose… - …, 2007 - rep.bioscientifica.com
In the present study, we examined the in vivo effects of estradiol (E 2) and progesterone on
cyclooxygenase (COX) 2, prostaglandin F synthase (PTGFS, also known as PGFS), and …

Sufficient progesterone-priming prior to estradiol stimulation is required for optimal induction of the cervical prostaglandin system in pregnant sheep at 0.7 gestations

WX Wu, T Coksaygan, K Chakrabarty… - Biology of …, 2005 - academic.oup.com
The purposes of this study were to determine the separate and interactive functions of
progesterone and estradiol in regulating the cervical prostaglandin (PG) system in pregnant …

Expression and regulation of the rat prostaglandin E2 receptor type 4 (EP4) in pregnant cervical tissue

EK Chien, C MacGregor - American journal of obstetrics and gynecology, 2003 - Elsevier
OBJECTIVE: Prostaglandins play an important role in the regulation of parturition and
cervical ripening. Prostaglandin E2 (PGE2)–induced tissue remodeling is mediated through …

The expression of ERα, OTR, cPLA2, COX-2, and PPARγ in the cervix of the ewe during the estrous cycle

L Falchi, RJ Scaramuzzi - Theriogenology, 2013 - Elsevier
The ovine cervix relaxes at estrus allowing easier entry of spermatozoa into the uterus. The
mechanism responsible for this relaxation is not fully elucidated and we hypothesized that …

An in vitro investigation of the actions of reproductive hormones on the cervix of the ewe in the follicular stage: the effects of 17β-estradiol, oxytocin, FSH, and …

L Falchi, RJ Scaramuzzi - Theriogenology, 2015 - Elsevier
During the periovulatory period, the cervix of the ewe relaxes and this mechanism is thought
to be mediated by oxytocin and prostaglandin E 2 (PGE 2) in response to increased …

Hormonal regulation of prostaglandin E2 receptors: localization and expression in rat cervical tissue

AC Hinton, PL Grigsby, BA Pitzer… - Reproductive …, 2010 - journals.sagepub.com
Prostaglandin E2 (PGE2) may regulate uterine activation and cervical ripening for labor
through specific contractile and relaxatory receptors (EP1-4). The aim of this study was to …