Background Gliomas present a significant economic burden and patient management
challenge. The 2021 WHO classification incorporates molecular parameters, which guide …

Gliomas can be classified into five molecular groups based on the status of IDH mutation,
1p/19q codeletion, and TERT promoter mutation, whereas they need to be obtained by …

Background Genotype status of glioma have important significance to clinical treatment and
prognosis. At present, there are few studies on the prediction of multiple genotype status in …

Our work reports implementation of a useful genetic diagnosis for the clinical managment of
patients with astrocytic tumors. We investigated 313 prospectively recruited diffuse astrocytic …

Background The purpose of this study was to develop a voxel-wise clustering method of
multiparametric magnetic resonance imaging (MRI) and 3, 4-dihydroxy-6-[18 F]-fluoro-L …

AIM To develop and validate an individualised radiomics–clinical nomogram for the
prediction of the isocitrate dehydrogenase 1 (IDH1) mutation status in primary glioblastoma …

Background Isocitrate dehydrogenase (IDH) mutation has diagnostic and prognostic values
in glioblastomas. Peritumoral invasion of glioma cells is a cardinal feature of glioblastomas …

Objectives To develop a radiomic signature to predict overall survival (OS) for high-grade
glioma (HGG), and construct a nomogram by combining selected radiomic, genetic and …

Objectives To develop a clinical radiomics–integrated model based on 18 F-
fluorodeoxyglucose positron emission tomography ([18F] FDG PET) and multi-modal MRI for …

Glioblastoma multiforme (GBM) typically exhibits substantial intratumoral heterogeneity at
both microscopic and radiological resolution scales. Diffusion Weighted Imaging (DWI) and …