BACKGROUND: Regular exercise has been recommended clinically for all individuals to
protect against hypertension but the underlying mechanisms are not fully elucidated. We …

Purpose: It is well established that high-load resistance exercise (HLRE) can stimulate
myofibrillar accretion. Additionally, recent studies suggest that HLRE can also stimulate …

Exercise is known to have numerous beneficial effects. Recent studies indicate that exercise
improves mitochondrial energetics not only in skeletal muscle but also in other tissues …

Mitochondria dysfunction is implicated in the pathogenesis of cardiovascular diseases
(CVD). Exercise training is potentially an effective non-pharmacological strategy to restore …

The mechanisms regulating oxidative phosphorylation during exercise remain poorly
defined; however, key mitochondrial proteins, including carnitine palmitoyltransferase-I (CPT …

Exercise is good for you. Elite athletes live longer than the general population (Teramoto &
Bungum, 2009). Physically active middle-aged men live on average 2.3 years longer than …

Ischemia-reperfusion-induced calcium overload and production of reactive oxygen species
can trigger apoptosis by promoting the release of proapoptotic factors via the mitochondrial …

Previous studies have shown that the aging vascular system undergoes pro-atherogenic
phenotypic changes, including increased oxidative stress and a pro-inflammatory shift in …

Cardiovascular disease risk and all-cause mortality are largely predicted by physical fitness.
Exercise stimulates vascular mitochondrial biogenesis through endothelial nitric oxide …

Cognitive performances are tightly associated with the maximal aerobic exercise capacity,
both of which decline with age. The benefits on mental health of regular exercise, which …