Effects of honokiol and magnolol on acute and inflammatory pain models in mice

YR Lin, HH Chen, CH Ko, MH Chan - Life Sciences, 2007 - Elsevier
The antinociceptive actions of honokiol and magnolol, two major bioactive constituents of
the bark of Magnolia officinalis, were evaluated using tail-flick, hot-plate and formalin tests in …

[HTML][HTML] Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain

YR Lin, HH Chen, YC Lin, CH Ko, MH Chan - Journal of Biomedical …, 2009 - Springer
The antinociceptive effects of honokiol and magnolol, two major bioactive constituents of the
bark of Magnolia officinalis, were investigated on animal paw licking responses and thermal …

[HTML][HTML] Antihyperalgesic properties of honokiol in inflammatory pain models by targeting of NF-κB and Nrf2 signaling

S Khalid, MZ Ullah, AU Khan, R Afridi… - Frontiers in …, 2018 - frontiersin.org
The present study investigates the possible anti-nociceptive effect of intraperitoneal (ip)
honokiol: a phenolic compound originally isolated from Magnolia officinalis, in acute and …

[HTML][HTML] Antinociceptive profile of levo-tetrahydropalmatine in acute and chronic pain mice models: role of spinal sigma-1 receptor

DW Kang, JY Moon, JG Choi, SY Kang, Y Ryu… - Scientific Reports, 2016 - nature.com
We have recently reported that repeated systemic treatments of extract from Corydalis
yanhusuo alleviate neuropathic pain and levo-tetrahydropalmatine (l-THP) is one of active …

[HTML][HTML] Antidepressant-like effect and mechanism of action of honokiol on the mouse lipopolysaccharide (LPS) depression model

B Zhang, PP Wang, KL Hu, LN Li, X Yu, Y Lu… - Molecules, 2019 - mdpi.com
There is growing evidence that neuroinflammation is closely linked to depression. Honokiol,
a biologically active substance extracted from Magnolia officinalis, which is widely used in …

Anti-nociceptive effects of magnolol via inhibition of TRPV1/P2Y and TLR4/NF-κB signaling in a postoperative pain model

MI Khan, A Khan, S Zafar, S Aslam, AU Khan, B Shal… - Life Sciences, 2023 - Elsevier
Aims The current study explored the anti-nociceptive activity of magnolol in post-incisional
inflammatory nociceptive pain. Main methods Preliminary, the anti-inflammatory, antioxidant …

Treatment with sulforaphane produces antinociception and improves morphine effects during inflammatory pain in mice

A Redondo, PAF Chamorro, G Riego, S Leánez… - Journal of Pharmacology …, 2017 - ASPET
The activation of nuclear factor erythroid 2-related factor 2 (Nrf2) exerts potent antioxidative
and anti-inflammatory effects; however, its participation in the modulation of chronic …

[HTML][HTML] The antinociceptive activity of harmicine on chemical-induced neurogenic and inflammatory pain models in mice

HM Spindola, DB Vendramini-Costa… - Pharmacology …, 2012 - Elsevier
Harmicine is a β-carboline alkaloid isolated and identified as a major active compound
present in many plant species and marine invertebrates. This alkaloid exhibits a wide …

Antinociceptive effect of meloxicam, in neurogenic and inflammatory nociceptive models in mice

ARS Santos, EMA Vedana, GAG De Freitas - Inflammation Research, 1998 - Springer
Objective: The antinociceptive effect of the new cyclooxygenase (COX)-2 inhibitor,
meloxicam, given intraperitoneally (ip), was assessed in different models of chemical and …

Bergapten inhibits chemically induced nociceptive behavior and inflammation in mice by decreasing the expression of spinal PARP, iNOS, COX-2 and inflammatory …

G Singh, A Kaur, J Kaur, MS Bhatti, P Singh… - …, 2019 - Springer
In continuation with our previous studies on osthole, bergapten, a closely related
furanocoumarin was investigated for its ameliorative effect on chemically induced …