Particulate matter in polluted air may increase biomarkers of inflammation in mouse brain

A Campbell, M Oldham, A Becaria, SC Bondy… - Neurotoxicology, 2005 - Elsevier
The etiology of neurodegenerative disorders is at present unknown. However, many of these
disorders are associated with an increase in oxidative and inflammatory events. Although a …

[HTML][HTML] The air we breathe: air pollution as a prevalent proinflammatory stimulus contributing to neurodegeneration

M Jankowska-Kieltyka, A Roman… - Frontiers in Cellular …, 2021 - frontiersin.org
Air pollution is regarded as an important risk factor for many diseases that affect a large
proportion of the human population. To date, accumulating reports have noted that …

Neurotoxicants Are in the Air: Convergence of Human, Animal, and In Vitro Studies on the Effects of Air Pollution on the Brain

LG Costa, TB Cole, J Coburn, YC Chang… - BioMed research …, 2014 - Wiley Online Library
In addition to increased morbidity and mortality caused by respiratory and cardiovascular
diseases, air pollution may also negatively affect the brain and contribute to central nervous …

Particulate matter induced enhancement of inflammatory markers in the brains of apolipoprotein E knockout mice

A Campbell, JA Araujo, H Li, C Sioutas… - … of nanoscience and …, 2009 - ingentaconnect.com
Exposure to air particulate matter (PM) present in urban environments have been shown to
induce systemic prooxidant and proinflammatory effects in apolipoprotein E knockout (ApoE …

Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology

LK Fonken, X Xu, ZM Weil, G Chen, Q Sun… - Molecular …, 2011 - nature.com
Particulate matter air pollution is a pervasive global risk factor implicated in the genesis of
pulmonary and cardiovascular disease. Although the effects of prolonged exposure to air …

The adverse effects of air pollution on the nervous system

S Genc, Z Zadeoglulari, SH Fuss… - Journal of toxicology, 2012 - Wiley Online Library
Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …

Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Exposure to inhaled particulate matter activates early markers of oxidative stress, inflammation and unfolded protein response in rat striatum

R Guerra, E Vera-Aguilar, M Uribe-Ramirez, G Gookin… - Toxicology letters, 2013 - Elsevier
To study central nervous system airborne PM related subchronic toxicity, SD male rats were
exposed for eight weeks to either coarse (32 μg/m 3), fine (178 μg/m 3) or ultrafine (107 …

Particulate matter, oxidative stress and neurotoxicity

SMJ MohanKumar, A Campbell, M Block, B Veronesi - Neurotoxicology, 2008 - Elsevier
Particulate matter (PM), a component of air pollution has been epidemiologically associated
with sudden deaths, cardiovascular and respiratory illnesses. The effects are more …

Neurotoxicity of traffic-related air pollution

LG Costa, TB Cole, J Coburn, YC Chang, K Dao… - Neurotoxicology, 2017 - Elsevier
The central nervous system is emerging as an important target for adverse health effects of
air pollution, where it may contribute to neurodevelopmental and neurodegenerative …