Despite breakthroughs in modern medical care, the incidence of cardiovascular disease
(CVD) is even more prevalent globally. Increasing epidemiologic evidence indicates that …

Haematopoiesis, the process of blood production, can be altered during the initiation or
progression of many diseases. Cardiovascular disease (CVD) has been shown to be heavily …

Hematopoietic stem cells (HSCs) generate all blood cell lineages responsible for tissue
oxygenation, life-long hematopoietic homeostasis and immune protection. In adulthood …

The cardiovascular and haematopoietic systems have fundamental inter-relationships
during development, as well as in health and disease of the adult organism. Although …

As the pathological basis of cardiovascular disease (CVD), atherosclerosis is featured as a
chronic inflammation. Hypercholesterolemia is an independent risk factor for CVD …

Myeloid cells are key contributors to tissue, immune and metabolic homeostasis and their
alteration fuels inflammation and associated disorders such as atherosclerosis. Conversely …

Diet, exercise, stress, and sleep are receiving attention as environmental modifiers of
chronic inflammatory diseases, including atherosclerosis, the culprit condition of myocardial …

Unhealthy diet, lack of exercise, psychosocial stress, and insufficient sleep are increasingly
prevalent modifiable risk factors for cardiovascular disease. Accumulating evidence …

Cardiovascular and oncological diseases represent the global major causes of death. For
both, a novel and far-reaching risk factor has been identified: clonal hematopoiesis (CH). CH …

Monocytes are a critical innate immune system cell type that serves homeostatic and
immunoregulatory functions. The Cell surface expression of CD14 and CD16 has historically …