Gastrointestinal (GI) cancer, referring to cancers of the digestive system such as colorectal
cancer (CRC), gastric cancer (GC), and liver cancer, is a major cause of cancer-related …

Genetic information that is transcribed from DNA to mRNA, and then translated from mRNA
to protein, is regulated by complex and sophisticated post-transcriptional mechanisms …

Simple Summary The profiles of miRNAs, tRNA-derived fragments and tRNAs from lung
cancer biopsy specimens indicate involvement of gene networks that modulate signaling …

Ars2 is a component of the nuclear cap-binding complex (CBC) that contributes to microRNA
biogenesis and is required for cellular proliferation. Little is known regarding the functional …

Cancer initiation and progression are defined by the behavior of cancer cells per se and the
development of tumor tissues, both of which are modulated by crosstalk between cancer …

The tumor-microenvironment (TME) is an amalgamation of various factors derived from
malignant cells and infiltrating host cells, including cells of the immune system. One of the …

Estrogen receptor alpha (ER α) activity is associated with increased cancer cell proliferation.
Studies aiming to understand the impact of ER α on cancer‐associated phenotypes have …

The heterogeneous population of cancer cells within a tumor mass interacts intricately with
the multifaceted aspects of the surrounding microenvironment. The reciprocal crosstalk …

Although activating mutations in RAS oncogenes are known to result in aberrant signaling
through multiple pathways, the role of microRNAs (miRNAs) in the Ras oncogenic program …

Members of the Msi family of RNA-binding proteins have recently emerged as potent
oncoproteins in a range of malignancies. MSI2 is highly expressed in hematopoietic …