[HTML][HTML] Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study

MW Sims, RM Tal-Singer, S Kierstein, AI Musani… - Respiratory …, 2008 - Springer
Abstract Background Surfactant protein D (SP-D), an innate immune molecule, plays an
important protective role during airway inflammation. Deficiency of this molecule induces …

Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD

DA Lomas, EK Silverman, LD Edwards… - European respiratory …, 2009 - Eur Respiratory Soc
Surfactant protein (SP)-D is a lung-derived protein that has been proposed as a biomarker
for inflammatory lung disease. Serum SP-D was evaluated as a biomarker for components of …

[HTML][HTML] Smoking reduces surfactant protein D and phospholipids in patients with and without chronic obstructive pulmonary disease

JM Moré, DR Voelker, LJ Silveira, MG Edwards… - BMC pulmonary …, 2010 - Springer
Abstract Background Pulmonary surfactant D (SP-D) has important regulatory functions for
innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary …

Surfactant protein D in human lung diseases

D Hartl, M Griese - European journal of clinical investigation, 2006 - Wiley Online Library
The lung is continuously exposed to inhaled pollutants, microbes and allergens. Therefore,
the pulmonary immune system has to defend against harmful pathogens, while an …

[HTML][HTML] Comprehensive characterisation of pulmonary and serum surfactant protein D in COPD

C Winkler, EN Atochina-Vasserman, O Holz… - Respiratory …, 2011 - Springer
Background Pulmonary surfactant protein D (SP-D) is considered as a candidate biomarker
for the functional integrity of the lung and for disease progression, which can be detected in …

Serum surfactant protein D during acute exacerbations of chronic obstructive pulmonary disease

TA Shakoori, DD Sin, F Ghafoor, S Bashir… - Disease …, 2009 - content.iospress.com
Background: There is a paucity of lung specific biomarkers to diagnose exacerbations of
chronic obstructive pulmonary disease (COPD) and to track their progression. Surfactant …

Airway surfactant protein D deficiency in adults with severe asthma

RMA Mackay, CL Grainge, LC Lau, C Barber, HW Clark… - Chest, 2016 - Elsevier
Background Surfactant protein D (SP-D) is an essential component of the innate immune
defense against pathogens within the airways. SP-D also regulates allergic inflammation …

Serum surfactant protein D is elevated in allergic patients

JG Koopmans, JS Van Der Zee… - Clinical & …, 2004 - Wiley Online Library
Background There is evidence that surfactant protein (SP)‐D is important in the innate, as
well as in the adaptive pulmonary immune response. Serum concentrations of SP‐D have …

[HTML][HTML] Value of serum and induced sputum surfactant protein-D in chronic obstructive pulmonary disease

BA Ozyurek, SS Ulasli, SS Bozbas, N Bayraktar… - Multidisciplinary …, 2013 - Springer
Abstract Background Surfactant Protein D (SP-D) is an important marker in chronic
obstructive pulmonary disease (COPD). Serum SP-D levels increase while lung production …

[HTML][HTML] Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium

J Xu, GK Singhera, DR Dorscheid - Respiratory Research, 2015 - Springer
Abstract Background Surfactant protein D (SP-D), a pattern recognition molecule, has been
shown to play roles in host defense such as opsonisation, aggregation of pathogens, and …