Pregabalin is a synthetic amino acid compound effective in clinical trials for the treatment of
post-herpetic neuralgia, diabetic peripheral neuropathy, generalized anxiety disorder and …

Pregabalin, a synthetic branched chain γ-amino acid with anticonvulsant, anxiolytic, and
analgesic activities, has been shown to bind with high affinity to the voltage-gated calcium …

Pregabalin (Lyrica™) is a new antiepileptic drug that is active in animal seizure models.
Pregabalin is approved in US and Europe for adjunctive therapy of partial seizures in adults …

Pregabalin,((S)-3-(aminomethyl)-5-methylhexanoic acid, also known as (S)-3-isobutyl
GABA, Lyrica™) is approved for treatment of certain types of peripheral neuropathic pain …

Pregabalin (Lyrica™) is a novel amino acid compound that binds with high affinity to the
alpha2–delta (α2–δ) auxiliary protein of voltage-gated calcium channels. In vivo, it potently …

Pregabalin is a specific ligand of the alpha 2-delta (α 2-δ) auxiliary subunit of voltage-gated
calcium channels. A growing body of evidence from studies of anxiety and pain indicate that …

Pregabalin is a potent ligand for the alpha‐2‐delta subunit of voltage‐gated calcium
channels in the central nervous system that exhibits potent anticonvulsant, analgesic, and …

This review provides a brief summary of what is known about the anxiolytic mechanism of
action of pregabalin, a highly selective, high-affinity ligand of the P/Q type of voltage-gated …

The α2δ auxiliary subunits (α2δ-1 and α2δ-2) of voltage-sensitive calcium channels are
thought to be the site of action of pregabalin (Lyrica), a drug that has been shown to be …

Pregabalin exhibits robust activity in preclinical assays indicative of potential antiepileptic,
anxiolytic, and antihyperalgesic clinical efficacy. It binds with high affinity to the α2-δ subunit …