Protective role of boron on hepatotoxicity and oxidative stress induced by trichloroacetic acid

C Wang, Y Shi, W Gu, C Wang, Y Xu, L Li… - Environmental Sciences …, 2023 - Springer
We conducted a comprehensive investigation into the protective roles of boron (B) against
trichloroacetic acid (TCA)-induced hepatotoxicity by assessing TCA exposure in vivo and …

[HTML][HTML] Dibromoacetic acid induced hepatotoxicity in mice through oxidative stress and toll-like receptor 4 signaling pathway activation

T Gong, W Jiang, Z Gao, Y Chen, S Gao - Oxidative Medicine and …, 2019 - hindawi.com
Dibromoacetic acid (DBA) is one of haloacetic acids, often as a by-product of disinfection in
drinking water. DBA is a multiple-organ carcinogen in rodent animals, but little research on …

[PDF][PDF] Oxidative damage to BV2 cells by trichloroacetic acid: protective role of boron via the p53 pathway

C Wang, W Huang, LI Li, C Wang, Y Shi, S Tang… - Biomed Environ …, 2022 - besjournal.com
This study aimed to investigate the neurotoxicity induced by trichloroacetic acid (TCA) and
the possible protective mechanisms of boron (B). Mouse BV2 cells were treated with TCA (0 …

Boron attenuated diethylnitrosamine induced hepatocellular carcinoma in C3H/HeN mice via alteration of oxidative stress and apoptotic pathway

Y Wei, J Yi, J Chen, H Huang, L Wu, X Yin… - Journal of Trace Elements …, 2022 - Elsevier
Background Reactive oxygen species (ROS) regulate various cellular signaling pathways
and play an important role in the occurrence and development of hepatocellular carcinoma …

Boron ameliorates fulminant hepatic failure by counteracting the changes associated with the oxidative stress

S Pawa, S Ali - Chemico-biological interactions, 2006 - Elsevier
Boron has well-defined biological effects and may be of therapeutic benefit. In the current
paper, the effect of boron in the form of borax was tested in experimental animal model of …

Protective effect of boric acid against carbon tetrachloride–induced hepatotoxicity in mice

S Ince, H Keles, M Erdogan, O Hazman… - Drug and chemical …, 2012 - Taylor & Francis
The protective effect of boric acid against liver damage was evaluated by its attenuation of
carbon tetrachloride (CCl4)-induced hepatotoxicity in mice. Male albino mice were treated …

Boron exhibits hepatoprotective effect together with antioxidant, anti-inflammatory, and anti-apoptotic pathways in rats exposed to aflatoxin B1

S Karatekeli, HH Demirel, F Zemheri-Navruz… - Journal of Trace …, 2023 - Elsevier
Background Aflatoxins are one of the important environmental factors that pose a risk to
living organisms. On the other hand, it has been indicated in research that boron intake has …

Sodium pentaborate prevents acetaminophen-induced hepatorenal injury by suppressing oxidative stress, lipid peroxidation, apoptosis, and inflammatory cytokines in …

E Aktas Senocak, N Utlu, S Kurt, S Kucukler… - … Trace Element Research, 2024 - Springer
Abstract Acetaminophen (N-acetyl-p-aminophenol, APAP, or paracetamol) is one of the
drugs that may be damaging to the kidneys and liver when used in excess. In this context, it …

Chlorogenic Acid Alleviated AFB1-Induced Hepatotoxicity by Regulating Mitochondrial Function, Activating Nrf2/HO-1, and Inhibiting Noncanonical NF-κB Signaling …

Q Wang, T Liu, M Koci, Y Wang, Y Fu, M Ma, Q Ma… - Antioxidants, 2023 - mdpi.com
Aflatoxin B1 (AFB1), a kind of mycotoxin, imposes acute or chronic toxicity on humans and
causes great public health concerns. Chlorogenic acid (CGA), a natural phenolic substance …

Endoplasmic reticulum stress is involved in 2, 4-dichlorophenol-induced hepatotoxicity

J Fu, X Zhang, P Chen, Y Zhang - The Journal of toxicological …, 2016 - jstage.jst.go.jp
2, 4-Dichlorophenol (2, 4-DCP) is an environmental pollutant exhibiting a wide spectrum of
toxic effects. We investigated the toxic effects and potential mechanisms underlying 2, 4 …