Engram size varies with learning and reflects memory content and precision
Memories are rarely acquired under ideal conditions, rendering them vulnerable to profound
omissions, errors, and ambiguities. Consistent with this, recent work using context fear …
omissions, errors, and ambiguities. Consistent with this, recent work using context fear …
Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse
Y Zaki, W Mau, C Cincotta, A Monasterio… - …, 2022 - nature.com
The formation and extinction of fear memories represent two forms of learning that each
engage the hippocampus and amygdala. How cell populations in these areas contribute to …
engage the hippocampus and amygdala. How cell populations in these areas contribute to …
Oscillatory and non‐oscillatory brain activity reflects fear expression in an immediate and delayed fear extinction task
P Bierwirth, MI Antov, U Stockhorst - Psychophysiology, 2023 - Wiley Online Library
Fear extinction is pivotal for inhibiting fear responding to former threat‐predictive stimuli. In
rodents, short intervals between fear acquisition and extinction impair extinction recall …
rodents, short intervals between fear acquisition and extinction impair extinction recall …
Adrenergic transmission facilitates extinction of conditional fear in mice
CK Cain, AM Blouin, M Barad - Learning & memory, 2004 - learnmem.cshlp.org
Extinction of classically conditioned fear, like its acquisition, is active learning, but little is
known about its molecular mechanisms. We recently reported that temporal massing of …
known about its molecular mechanisms. We recently reported that temporal massing of …
Fear reduction without fear through reinforcement of neural activity that bypasses conscious exposure
Fear conditioning is a fundamentally important and preserved process across species,. In
humans it is linked to fear-related disorders such as phobias and post-traumatic stress …
humans it is linked to fear-related disorders such as phobias and post-traumatic stress …
[HTML][HTML] From extinction learning to anxiety treatment: Mind the gap
JK Carpenter, M Pinaire, SG Hofmann - Brain sciences, 2019 - mdpi.com
Laboratory models of extinction learning in animals and humans have the potential to
illuminate methods for improving clinical treatment of fear-based clinical disorders. However …
illuminate methods for improving clinical treatment of fear-based clinical disorders. However …
Analysis of coherent activity between retrosplenial cortex, hippocampus, thalamus, and anterior cingulate cortex during retrieval of recent and remote context fear …
KA Corcoran, BJ Frick, J Radulovic, LM Kay - Neurobiology of Learning and …, 2016 - Elsevier
Memory for contextual fear conditioning relies upon the retrosplenial cortex (RSC)
regardless of how long ago conditioning occurred, whereas areas connected to the RSC …
regardless of how long ago conditioning occurred, whereas areas connected to the RSC …
[HTML][HTML] Enhanced synchronization between prelimbic and infralimbic cortices during fear extinction learning
M Watanabe, A Uematsu, JP Johansen - Molecular Brain, 2021 - Springer
The ability to extinguish aversive memories when they are no longer associated with danger
is critical for balancing survival with competing adaptive demands. Previous studies …
is critical for balancing survival with competing adaptive demands. Previous studies …
Reappraisal is less effective than distraction in downregulation of neural responses to physical threats—An event‐related potential investigation
Evolutionary threats (ETs), such as predatory animals and heights, elicit stronger fear
responses and are more often the subject of specific phobias, as compared to modern …
responses and are more often the subject of specific phobias, as compared to modern …
Fear extinction relies on ventral hippocampal safety codes shaped by the amygdala
R Nguyen, K Koukoutselos, T Forro, S Ciocchi - Science Advances, 2023 - science.org
Extinction memory retrieval is influenced by spatial contextual information that determines
responding to conditioned stimuli (CS). However, it is poorly understood whether contextual …
responding to conditioned stimuli (CS). However, it is poorly understood whether contextual …