Evidence from epidemiological studies and a human intervention trial indicates that
selenium (Se) may have chemopreventive activity in humans. This report summarizes a …

The element selenium (Se) was identified, nearly 40 years ago, as being essential in the
nutrition of animals and humans. In addition, antitumorigenic effects of Se compounds have …

The hypothesis that a dietary supplement of selenium (Se) may reduce cancer risk was
tested experimentally in humans. Patients with histories of basal/squamous cell carcinomas …

Epidemiological and animal studies have implicated selenium as a cancer-protective agent.
These reports have generated much enthusiasm for human intervention studies with the …

Cancer is the second leading cause of death in the United States, resulting in more than 1
million deaths per year, and is projected to overtake heart disease as the leading cause of …

Publisher Summary This chapter focuses on the role that selenium (Se) compounds play in
the inhibition or slowing of the induction of cancer by chemicals and other agents. Se has …

The element selenium (Se) was recognized only 40 years ago as being essential in the
nutrition of animals and humans. It is recognized as being an essential component of a …

The article reviews the progress in basic research of selenium and cancer prevention during
the past decade. Special emphasis is placed on the following four major areas of discussion …

Experimental studies with rodents indicate that selenium supplementation at levels above
the dietary requirement is capable of protecting against tumorigenesis induced by chemical …

Nonexperimental studies suggest that individuals with higher selenium (Se) status are at
decreased risk of cancer. The Nutritional Prevention of Cancer (NPC) study randomized …