Curcumin and cancer stem cells: curcumin has asymmetrical effects on cancer and normal stem cells

PP Sordillo, L Helson - Anticancer Research, 2015 - ar.iiarjournals.org
Curcumin has been shown to have numerous cytotoxic effects on cancer stem cells (CSCs).
This is due to its suppression of the release of cytokines, particularly interleukin (IL)-6, IL-8 …

Targeting cancer stem cells by curcumin and clinical applications

Y Li, T Zhang - Cancer letters, 2014 - Elsevier
Curcumin is a well-known dietary polyphenol derived from the rhizomes of turmeric, an
Indian spice. The anticancer effect of curcumin has been demonstrated in many cell and …

The role of cancer stem cells in the anti‐carcinogenicity of curcumin

L Norris, A Karmokar, L Howells… - Molecular nutrition & …, 2013 - Wiley Online Library
Many cancers contain cell subpopulations that display characteristics of stem cells. These
cells are characterised by their ability to self‐renew, form differentiated progeny and develop …

Curcumin: a promising agent targeting cancer stem cells

S Zang, T Liu, J Shi, L Qiao - Anti-Cancer Agents in Medicinal …, 2014 - ingentaconnect.com
Cancer stem cells are a subset of cells that are responsible for cancer initiation and relapse.
They are generally resistant to the current anticancer agents. Successful anticancer therapy …

The molecular mechanisms of curcumin's inhibitory effects on cancer stem cells

E Zendehdel, E Abdollahi… - Journal of Cellular …, 2019 - Wiley Online Library
Curcumin is a dietary polyphenol and a bioactive phytochemical that possesses anti‐
inflammatory, antioxidant, anticancer, and chemopreventive properties, which make it …

Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?

J Ravindran, S Prasad, BB Aggarwal - The AAPS journal, 2009 - Springer
Cancer is a hyperproliferative disorder that is usually treated by chemotherapeutic agents
that are toxic not only to tumor cells but also to normal cells, so these agents produce major …

[HTML][HTML] Anticancer effect of curcumin on breast cancer and stem cells

HT Liu, YS Ho - Food science and human wellness, 2018 - Elsevier
Numerous studies have shown that curcumin, a natural compound, exerts anticancer effects
by inhibiting cancer cell proliferation and metastasis and by inducing cell cycle arrest and …

Curcumin mediates anticancer effects by modulating multiple cell signaling pathways

AB Kunnumakkara, D Bordoloi, C Harsha… - Clinical …, 2017 - portlandpress.com
Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …

Effects of curcumin on stem-like cells in human esophageal squamous carcinoma cell lines

TN Almanaa, ME Geusz, RJ Jamasbi - BMC complementary and …, 2012 - Springer
Background Many cancers contain cell subpopulations that display characteristics of stem
cells. Because these cancer stem cells (CSCs) appear to provide resistance to chemo …

[PDF][PDF] Curcumin: from exotic spice to modern anticancer drug

G Sa, T Das, S Banerjee, J Chakraborty - Al Ameen J Med Sci, 2010 - researchgate.net
Inhibition of defined molecular steps of tumourigenesis by natural non-toxic compounds may
be an efficient means to tackle the population cancer burden. Extensive research has …