Incidence and predictors of bleeding after contemporary thrombolytic therapy for myocardial infarction

SD Berkowitz, CB Granger, KS Pieper, KL Lee… - Circulation, 1997 - Am Heart Assoc
Background Although the benefit of thrombolytic therapy in reducing mortality in acute
myocardial infarction is well established, the types of bleeding and risk factors for bleeding …

Translation of clinical trials into practice: a European population-based study of the use of thrombolysis for acute myocardial infarction

KL Woods… - The Lancet, 1996 - Elsevier
Background There is conclusive evidence from clinical trials that thrombolytic therapy
reduces mortality in acute myocardial infarction (AMI). But still only a minority of patients …

Comparative efficacy of thrombolytics in acute myocardial infarction: a systematic review

Y Dundar, R Hill, R Dickson, T Walley - Qjm, 2003 - academic.oup.com
Background: The comparative clinical effectiveness of new (reteplase, tenecteplase) vs.
older (alteplase, streptokinase) thrombolytic agents in the treatment of acute myocardial …

[HTML][HTML] An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction

Gusto Investigators - New England Journal of Medicine, 1993 - Mass Medical Soc
Background The relative efficacy of streptokinase and tissue plasminogen activator and the
roles of intravenous as compared with subcutaneous heparin as adjunctive therapy in acute …

[HTML][HTML] The risk of stroke in patients with acute myocardial infarction after thrombolytic and antithrombotic treatment

AP Maggioni, MG Franzosi, E Santoro… - … England Journal of …, 1992 - Mass Medical Soc
Background. Many trials in patients with acute myocardial infarction have demonstrated that
thrombolytic therapy is not associated with an excessive risk of stroke, as compared with …

Optimal utilization of thrombolytic therapy for acute myocardial infarction: concepts and controversies

CL Grines, AN DeMaria - Journal of the American College of Cardiology, 1990 - Elsevier
Timely administration of thrombolytic therapy decreases myocardial infarct size, lessens the
incidence of congestive heart failure and improves survival. However, available data …

[HTML][HTML] Clinical importance of thrombocytopenia occurring in the hospital phase after administration of thrombolytic therapy for acute myocardial infarction

RA Harrington, DC Sane, RM Califf, KN Sigmon… - Journal of the American …, 1994 - Elsevier
Objectives. The purpose of this study was to examine the incidence and clinical implications
of thrombocytopenia that occurs in hospital after administration of thrombolytic therapy for …

Thrombolysis and adjunctive therapy in acute myocardial infarction: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

V Menon, RA Harrington, JS Hochman, CP Cannon… - Chest, 2004 - Elsevier
This chapter about antithrombotic therapy for acute myocardial infarction (MI) is part of the
Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based …

Thrombolytic therapy for acute myocardial infarction: a review

CB Granger, RM Califf, EJ Topol - Drugs, 1992 - Springer
In the past 10 years, thrombolytics have become standard therapy for acute myocardial
infarction. Although the ability of streptokinase to lyse clot was first recognised in the 1930s …

Risk factors for in-hospital nonhemorrhagic stroke in patients with acute myocardial infarction treated with thrombolysis: results from GUSTO-I

KW Mahaffey, CB Granger, MA Sloan, TD Thompson… - Circulation, 1998 - Am Heart Assoc
Background—Nonhemorrhagic stroke occurs in 0.1% to 1.3% of patients with acute
myocardial infarction who are treated with thrombolysis, with substantial associated mortality …