[HTML][HTML] Direct cardiovascular effects of glucagon like peptide-1

A Sheikh - Diabetology & Metabolic Syndrome, 2013 - Springer
Current gold standard therapeutic strategies for T2DM target insulin resistance or β cell
dysfunction as their core mechanisms of action. However, the use of traditional anti-diabetic …

GLP-1 agonist-based therapies: an emerging new class of antidiabetic drug with potential cardioprotective effects

M Sulistio, C Carothers, M Mangat, M Lujan… - Current atherosclerosis …, 2009 - Springer
Cardiovascular disease is a leading cause of death in the United States and across the
world, and better therapies are constantly being sought to improve patient outcomes. Recent …

Mechanism of cardiovascular disease benefit of glucagon-like peptide 1 agonists

J Reed, V Kanamarlapudi, S Bain - … Endocrinology & Metabolism, 2018 - journals.lww.com
Abstract Glucagon-like peptide 1 (GLP-1)-based therapies reduce hyperglycaemia in type 2
diabetes. Diabetes cardiovascular comorbidity remains prevalent, although current …

Glucagon‐like peptide‐1‐based therapies and cardiovascular disease: looking beyond glycaemic control

P Anagnostis, VG Athyros, F Adamidou… - Diabetes, Obesity …, 2011 - Wiley Online Library
Type 2 diabetes mellitus is a well‐established risk factor for cardiovascular disease (CVD).
New therapeutic approaches have been developed recently based on the incretin …

Cardiovascular effects of GLP‐1 and GLP‐1‐based therapies: implications for the cardiovascular continuum in diabetes?

M Burgmaier, C Heinrich, N Marx - Diabetic medicine, 2013 - Wiley Online Library
Diabet. Med. 30, 289–299 (2013) Abstract Aims Glucagon‐like peptide‐1 receptor agonists
and inhibitors of dipeptidyl peptidase‐4 that increase glucagon‐like peptide‐1 plasma …

Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action

JR Ussher, DJ Drucker - Nature Reviews Cardiology, 2023 - nature.com
Type 2 diabetes mellitus (T2DM) and obesity are metabolic disorders characterized by
excess cardiovascular risk. Glucagon-like peptide 1 (GLP1) receptor (GLP1R) agonists …

Potential cardioprotective action of GLP-1: from bench to bedside

KN Aronis, MA Tsoukas… - Metabolism-Clinical …, 2014 - metabolismjournal.com
Type 2 diabetes mellitus (T2DM) is a highly prevalent disease that is associated with
development of atherosclerosis and an increase in all-cause mortality. Treatment options for …

Selective targeting of glucagon‐like peptide‐1 signalling as a novel therapeutic approach for cardiovascular disease in diabetes

M Tate, A Chong, E Robinson… - British journal of …, 2015 - Wiley Online Library
Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone whose glucose‐dependent
insulinotropic actions have been harnessed as a novel therapy for glycaemic control in type …

[HTML][HTML] Recent advances in understanding the role of glucagon-like peptide 1

J Reed, SC Bain, V Kanamarlapudi - F1000Research, 2020 - ncbi.nlm.nih.gov
The discovery that glucagon-like peptide 1 (GLP-1) mediates a significant proportion of the
incretin effect during the postprandial period and the subsequent observation that GLP-1 …

Glucagon‐like peptide‐1 (GLP‐1) receptor agonists and their cardiovascular benefits—The role of the GLP‐1 receptor

J Helmstädter, K Keppeler, L Küster… - British journal of …, 2022 - Wiley Online Library
Cardiovascular outcome trials revealed cardiovascular benefits for type 2 diabetes mellitus
patients when treated with long‐acting glucagon‐like peptide‐1 (GLP‐1) receptor agonists …