The processes that regulate T cell memory generation are important for therapeutic design
and the immune response to disease. However, what allows a subset of effector T cells to …

Immunological memory provides rapid protection to pathogens previously encountered
through infection or vaccination. CD 4 T‐cells play a central role in all adaptive immune …

Our knowledge about the kinetics and dynamics of complex pathogen‐specific CD8+ T cell
responses and the in vivo development of CD8+ memory T cells has increased substantially …

The duration of infection and the quantity of Ag presented in vivo are commonly assumed to
influence, if not determine, the magnitude of T cell responses. Although the cessation of in …

Memory CD8+ T cells can be divided into two subsets, central memory (T CM) and effector
memory (T EM) CD8+ T cells. We found that CD30, a member of the TNFR-associated factor …

Memory T cells, including the well-known CD4+ and CD8+ T cells, are central components
of the acquired immune system and are the basis for successful vaccination. After infection …

Memory T cells are critical for the control of intracellular pathogens and require few signals
for maintenance; however, erosion of established preexisting memory CD8+ T cells has …

In this study, we compared the proliferation and differentiation of Ag-specific CD4 and CD8 T
cells following Listeria infection. Our results show that CD4 T cells responding to infection …

Induction and maintenance of T cell memory is critical for the control of intracellular
pathogens and tumors. Memory T cells seem to require few “maintenance signals,” though …

Pathogen-specific CD8+ T cells expand in number after infection and then their numbers
invariably contract by 90–95%, leaving a stable memory cell pool. The chief features of this …