The peroxisome proliferator-activated receptor co-activator-1α (PGC1α) belongs to a family
of transcriptional regulators, which act as co-activators for a number of transcription factors …

Amyloid-β (Aβ) is the core component of amyloid plaques of Alzheimer's disease (AD).
Recent evidence has confirmed that Aβ triggers neurodegeneration by dramatically …

Alzheimer's disease (AD) is a neurodegenerative disorder and its reported
pathophysiological features in the brain include the deposition of amyloid beta peptide …

Recently, growing evidence has demonstrated that peroxisome proliferator activated
receptor γ (PPARγ) coactivator-1α (PGC-1α) is a superior transcriptional regulator that acts …

The onset and mechanisms underlying neurodegenerative diseases remain uncertain. The
main features of neurodegenerative diseases have been related with cellular and molecular …

Peroxisome proliferator-activated receptor-gamma coactivator-1α (PGC-1α) transcriptional
coactivators are key regulators of energy metabolism-related genes and are expressed in …

Objectives To explore mechanisms through which altered peroxisome proliferator–activated
receptor γ coactivator 1α (PGC-1α) expression may influence Alzheimer disease (AD) …

The peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) interacts with
various transcription factors involved in energy metabolism and in the regulation of …

The peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a well-known
transcriptional coactivator involved in mitochondrial biogenesis. PGC-1α is implicated in the …

Neurodegenerative disorders (NDDs) are characterized by progressive loss of selectively
vulnerable neuronal populations and myelin sheath, leading to behavioral and cognitive …