Silibinin in vitro protects A549 cells from staphylococcus aureus-mediated injury and in vivo alleviates the lung injury of staphylococcal pneumonia
X Wang, J Dong, X Dai, Y Zhang, J Wang, H Li… - Planta …, 2013 - thieme-connect.com
In this study, hemolysis, Western blot, and real-time RT-PCR assays were performed to
evaluate silibininʼs activity against S. aureus α-toxin secretion. In addition, live/dead cell …
evaluate silibininʼs activity against S. aureus α-toxin secretion. In addition, live/dead cell …
[HTML][HTML] Concentration-dependent dual effects of silibinin on kanamycin-induced cells death in Staphylococcus aureus
JY Cai, J Li, YN Hou, K Ma, GD Yao, WW Liu… - Biomedicine & …, 2018 - Elsevier
Silibinin has dual effects on bacteria, depending on the concentrations or living contexts.
The mechanism of either action has not yet been elucidated. Present study suggests that …
The mechanism of either action has not yet been elucidated. Present study suggests that …
Reactive oxygen species depletion by silibinin stimulates apoptosis-like death in escherichia coli
B Lee, DG Lee - Journal of Microbiology and Biotechnology, 2017 - koreascience.kr
Silibinin is the major active component of silymarin, extracted from the medicinal plant
Silybum marianum. Silibinin has potent antibacterial activity; however, the exact mechanism …
Silybum marianum. Silibinin has potent antibacterial activity; however, the exact mechanism …
[HTML][HTML] Inhibition of Phagocytosis by Silibinin in Mouse Macrophages
KH Sun, MY Lee, YJ Jeon - Current Issues in Molecular Biology, 2023 - mdpi.com
This study investigated the effects of silibinin, derived from milk thistle (Silybum marianum),
on lipopolysaccharide (LPS)-induced morphological changes in mouse macrophages …
on lipopolysaccharide (LPS)-induced morphological changes in mouse macrophages …
[HTML][HTML] Silibinin protects Staphylococcus aureus from UVC-induced bactericide via enhanced generation of reactive oxygen species
JY Cai, YY Wang, K Ma, YN Hou, J Li, GD Yao… - RSC …, 2017 - pubs.rsc.org
Silibinin is a major bioactive component of silymarin extracted from the milk thistle Silybum
marianum. Silibinin has therapeutic potential for a wide variety of applications including …
marianum. Silibinin has therapeutic potential for a wide variety of applications including …
Synergistic effects between silibinin and antibiotics on methicillin‐resistant Staphylococcus aureus isolated from clinical specimens
HK Kang, HY Kim, JD Cha - Biotechnology journal, 2011 - Wiley Online Library
Methicillin‐resistant Staphylococcus aureus (MRSA) is a dangerous microorganism, and
creates serious medical problems. It causes many types of infections in humans and often …
creates serious medical problems. It causes many types of infections in humans and often …
[PDF][PDF] Silibinin promotes the apoptosis of gastric cancer BGC823 cells through caspase pathway
R Li, J Yu, C Wang - J BUON, 2017 - jbuon.com
Purpose: To investigate the effects of silibinin, a natural compound, on the proliferation and
apoptosis of BGC-823 gastric cancer cell line and to figure out the relevant pathways …
apoptosis of BGC-823 gastric cancer cell line and to figure out the relevant pathways …
[HTML][HTML] The ameliorative effect of silibinin against radiation-induced lung injury: protection of normal tissue without decreasing therapeutic efficacy in lung cancer
Y Son, HJ Lee, JK Rho, SY Chung, CG Lee… - BMC pulmonary …, 2015 - Springer
Background Silibinin has been known for its role in anti-cancer and radio-protective effect.
Radiation therapy for treating lung cancer might lead to late-phase pulmonary inflammation …
Radiation therapy for treating lung cancer might lead to late-phase pulmonary inflammation …
Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells
Recently, we reported that silibinin inhibits primary lung tumor growth and progression in
mice and down-regulates inducible nitric oxide synthase (iNOS) expression in tumors; …
mice and down-regulates inducible nitric oxide synthase (iNOS) expression in tumors; …
Eriodictyol protects against Staphylococcus aureus-induced lung cell injury by inhibiting alpha-hemolysin expression
H Xuewen, O Ping, Y Zhongwei, Y Zhongqiong… - World Journal of …, 2018 - Springer
Staphylococcus aureus (S. aureus) is a common pathogenic bacterium that causes various
diseases in both humans and animals. With the increased prevalence of methicillin-resistant …
diseases in both humans and animals. With the increased prevalence of methicillin-resistant …