Methicillin-resistant Staphylococcus aureus (MRSA) is a troublesome pathogen that poses a
global threat to public health. Shikonin (SKN) isolated from Lithospermum erythrorhizon (L …

Context: Multiple drug resistance is the major obstacle to conventional chemotherapy.
Silibinin, a nontoxic naturally occurring compound, has anticancer activity and can increase …

Background: Silibinin (SB), the main component of Silymarin (SM), is a natural substance
obtained from the seeds of the milk thistle. SM contains up to 70% of SB as two isoforms: A …

Multi-drug resistant Staphylococcus aureus infection is still a serious threat to global health.
Therefore, there is an urgent need to develop new antibacterial agents based on virulence …

The emergence and dissemination of bacterial infections is paralyzing our public health
systems worldwide. Worse still, there are no effective antibiotics against bacterial toxins …

Silibinin suppresses the growth of many cancers; however, its efficacy against pancreatic
cancer has not been evaluated in established preclinical models. Here, we investigated in …

AIMS: We previously reported that tetrapeptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-
SDKP) inhibited pulmonary inflammation and fibrosis in SiO2-induced silicosis. This study …

Silicosis is an occupational lung disease caused by inhaling silica dust. The disease is
characterized by early lung inflammation and late irreversible pulmonary fibrosis. Here we …

Tetrandrine is an alkaloid obtained from the root of a medicinal herb which is employed in
China as a treatment for silicosis. One proposed mechanism for the development of silica …

Background: Silibinin, a naturally-occurring flavonoid produced by milk thistle, possesses
antioxidant, anti-inflammatory and cancer-preventive activities. In the current study, we …