Abstract Treatment options for COVID‐19, caused by SARS‐CoV‐2, remain limited.
Understanding viral pathogenesis at the molecular level is critical to develop effective …

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
devastated the global economy and claimed more than 1.7 million lives, presenting an …

Protein–protein interactions (PPIs) are the vital engine of cellular machinery. After virus entry
in host cells the global organization of the viral life cycle is strongly regulated by the …

Studying viral–host protein–protein interactions can facilitate the discovery of therapies for
viral infection. We use high-throughput yeast two-hybrid experiments and mass spectrometry …

An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19
respiratory disease, has infected over 290,000 people since the end of 2019, killed over …

Human coronaviruses (hCoVs) have become a threat to global health and society, as
evident from the SARS outbreak in 2002 caused by SARS-CoV-1 and the most recent …

Host–virus protein–protein interactions play key roles in the life cycle of severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2). We conducted a comprehensive …

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative
agent of coronavirus disease 2019 (COVID-19), was declared a pandemic infection in March …

Key steps of viral replication take place at host cell membranes, but the detection of
membrane-associated protein-protein interactions using standard affinity-based approaches …

Viral replication is dependent on interactions between viral polypeptides and host proteins.
Identifying virus-host protein interactions can thus uncover unique opportunities for …