Dysregulation of m6A RNA methylation regulators in colorectal cancer: clinical implication as prognostic biomarkers and potential therapeutic targets
R Kandimalla, F Gao, C Ruan, M Hsieh, X Wang… - Cancer Research, 2018 - AACR
Purpose Among more than 100 known post-transcriptional modifications, N6-
Methyladenosine (m6A) represents the most prevalent internal modification in mammalian …
Methyladenosine (m6A) represents the most prevalent internal modification in mammalian …
Novel evidence for m6A methylation regulators as prognostic biomarkers and potential therapeutic targets in gastric cancer
Abstract Purpose: N6-methyladenosine (m6A) post-transcriptional RNA modification
represents the most abundant epigenetic alteration in eukaryotic cells. These m6A …
represents the most abundant epigenetic alteration in eukaryotic cells. These m6A …
N6-methyladenosine (m6A) RNA modification in gastrointestinal tract cancers: roles, mechanisms, and applications
B Hu, X Wang, XY Gu, C Zou, Z Gao, H Zhang, Y Fan - Molecular cancer, 2019 - Springer
Analogous to DNA methylation and histone modification, RNA modification, as another
epigenetic layer, plays an important role in many diseases, especially in tumours. As the …
epigenetic layer, plays an important role in many diseases, especially in tumours. As the …
The role of m6A RNA methylation in human cancer
XY Chen, J Zhang, JS Zhu - Molecular cancer, 2019 - Springer
Abstract N 6-methyladenosine (m 6 A) is identified as the most common, abundant and
conserved internal transcriptional modification, especially within eukaryotic messenger …
conserved internal transcriptional modification, especially within eukaryotic messenger …
Aberrant expression of m6A mRNA methylation regulators in colorectal adenoma and adenocarcinoma
D Kuai, S Zhu, H Shi, R Yang, T Liu, H Liu, L Min… - Life sciences, 2021 - Elsevier
Background As the most prevalent post-transcriptional mRNA modification in eukaryotes, N6-
Methyladenosine (m 6 A) is closely linked to the occurrence and development of colorectal …
Methyladenosine (m 6 A) is closely linked to the occurrence and development of colorectal …
Expression and prognostic characteristics of m6A RNA methylation regulators in colon cancer
L Huang, J Zhu, W Kong, P Li, S Zhu - International Journal of Molecular …, 2021 - mdpi.com
Colon cancer is a common and leading cause of death and malignancy worldwide. N6-
methylation of adenosine (m6A) is the most common reversible mRNA modification in …
methylation of adenosine (m6A) is the most common reversible mRNA modification in …
Emerging roles of RNA methylation in gastrointestinal cancers
RNA methylation has emerged as a fundamental process in epigenetic regulation.
Accumulating evidences indicate that RNA methylation is essential for many biological …
Accumulating evidences indicate that RNA methylation is essential for many biological …
The potential role of RNA N6-methyladenosine in Cancer progression
T Wang, S Kong, M Tao, S Ju - Molecular cancer, 2020 - Springer
Abstract N6-methyladenosine (m6A) is considered the most common, abundant, and
conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA) …
conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA) …
Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers
D Ramasamy, M Thippannah, HRP Maharajan… - Molecular Biology …, 2024 - Springer
Abstract Background N6-methyladenosine (m6A) is a prevalent and crucial RNA methylation
modification that plays a significant role in various biological and pathological processes …
modification that plays a significant role in various biological and pathological processes …
The predictive significance of a 5-m6A RNA methylation regulator signature in colorectal cancer
D Zhang, G Wu, L Yang, Q Wu, L Yuan - Heliyon, 2023 - cell.com
Colorectal cancer attacks the colon or rectum, with increasing morbidity and mortality
globally. The RNA modification 6-methyladenine (m6A) is related to RNA modifications …
globally. The RNA modification 6-methyladenine (m6A) is related to RNA modifications …
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