[HTML][HTML] Audit of empirical antibiotic therapy for sepsis and the impact of early multidisciplinary consultation on patient outcomes.

V D'Onofrio, A Meersman, K Magerman… - International Journal of …, 2021 - Elsevier
Objectives To perform an audit of empirical antibiotic therapy (EAT) of sepsis at the
emergency department and to analyse the impact of an antimicrobial stewardship (AMS) …

Impact of Appropriate Empirical Antibiotic Treatment on the Clinical Response of Septic Patients in Intensive Care Unit: A Single-Center Observational Study

M Tićac, T Grubić Kezele, M Bubonja Šonje - Antibiotics, 2024 - mdpi.com
The appropriate antibiotic treatment of patients with bacterial sepsis in the intensive care unit
(ICU) remains a challenge. Considering that current international guidelines recommend 7 …

A role for antimicrobial stewardship in clinical sepsis pathways: a prospective interventional study

J Burston, S Adhikari, A Hayen, H Doolan… - infection control & …, 2017 - cambridge.org
OBJECTIVETo evaluate the impact of early infectious diseases (ID) antimicrobial
stewardship (AMS) intervention on inpatient sepsis antibiotic management …

Development of quality indicators for antimicrobial treatment in adults with sepsis

CMA van den Bosch, MEJL Hulscher, S Natsch… - BMC infectious …, 2014 - Springer
Background Outcomes in patients with sepsis are better if initial empirical antimicrobial use
is appropriate. Several studies have shown that adherence to guidelines dictating …

[HTML][HTML] Ignorance of pre-ED healthcare setting is a factor leading to inappropriate initial antibiotic treatment of sepsis in ED and poor outcomes in ICU

WL Su, HA Shui, MY Peng - Journal of microbiology, immunology and …, 2020 - Elsevier
Objectives Appropriate initial antibiotic therapy is critical for successfully treating sepsis. In
the emergency department (ED), clinicians often rely on septic symptoms to guide empirical …

Evaluation of an opt-out protocol for antibiotic de-escalation in patients with suspected sepsis: a multicenter, randomized, controlled trial

RW Moehring, ME Yarrington… - Clinical Infectious …, 2023 - academic.oup.com
Background Sepsis guidelines recommend daily review to de-escalate or stop antibiotics in
appropriate patients. This randomized, controlled trial evaluated an opt-out protocol to …

Early antimicrobial stewardship team intervention on appropriateness of antimicrobial therapy in suspected sepsis: a randomized controlled trial

Z Rashidzada, KA Cairns, TN Peel… - JAC-Antimicrobial …, 2021 - academic.oup.com
Objectives There has been concern that the imperative to administer rapid antimicrobials in
septic patients may result in inappropriate antimicrobial use. We aimed to determine the …

A modified Delphi approach to develop a trial protocol for antibiotic de-escalation in patients with suspected sepsis

ME Yarrington, RW Moehring, MZ David… - Antimicrobial …, 2021 - cambridge.org
Background: Early administration of antibiotics in sepsis is associated with improved patient
outcomes, but safe and generalizable approaches to de-escalate or discontinue antibiotics …

Strengthening sepsis care at a tertiary care teaching hospital in New Delhi, India

C Malhotra, A Kumar, AK Sahu… - BMJ open …, 2021 - bmjopenquality.bmj.com
Introduction Failure of early identification of sepsis in the emergency department (ED) leads
to significant delays in antibiotic administration which adversely affects patient outcomes …

Implementation of guidelines for sepsis management in emergency departments: a systematic review

Y Sungkar, J Considine, A Hutchinson - Australasian emergency care, 2018 - Elsevier
Introduction Timely, evidence-based emergency care for sepsis saves lives. The primary aim
of this systematic review was to examine the effect of implementation of guidelines for the …