Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10)

K Donaldson, V Stone, PJA Borm, LA Jimenez… - Free Radical Biology …, 2003 - Elsevier
This review focuses on the potential role that oxidative stress plays in the adverse effects of
PM10. The central hypothesis is that the ability of PM10 to cause oxidative stress underlies …

Roles of oxidative stress in signaling and inflammation induced by particulate matter

F Mazzoli-Rocha, S Fernandes… - Cell biology and …, 2010 - Springer
This review reports the role of oxidative stress in impairing the function of lung exposed to
particulate matter (PM). PM constitutes a heterogeneous mixture of various types of particles …

Water‐insoluble fraction of airborne particulate matter (PM10) induces oxidative stress in human lung epithelial A549 cells

S Yi, F Zhang, F Qu, W Ding - Environmental toxicology, 2014 - Wiley Online Library
Exposure to ambient airborne particulate matter (PM) with an aerodynamic diameter less
than 10 μm (PM10) links with public health hazards and increases risk for lung cancer and …

Redox and inflammatory mechanisms linking air pollution particulate matter with cardiometabolic derangements

T Marchini - Free Radical Biology and Medicine, 2023 - Elsevier
Air pollution is the largest environmental risk factor for disease and premature death. Among
the different components that are present in polluted air, fine particulate matter below 2.5 μm …

Activation of NF-κB by PM10 occurs via an iron-mediated mechanism in the absence of IκB degradation

LA Jimenez, J Thompson, DA Brown, I Rahman… - Toxicology and applied …, 2000 - Elsevier
Exposureto particulate air pollution (PM10) is associated with exacerbations of respiratory
diseases and increased cardiopulmonary mortality. PM10 induces lung inflammation in rats …

Function of PM2. 5 in the pathogenesis of lung cancer and chronic airway inflammatory diseases

R Li, R Zhou, J Zhang - Oncology letters, 2018 - spandidos-publications.com
Previous research has identified that air pollution is associated with various respiratory
diseases, but few studies have investigated the function served by particulate matter 2.5 …

Particulate matter physicochemistry and toxicology: In search of causality—A critical perspective

KL Dreher - Inhalation Toxicology, 2000 - Taylor & Francis
Results from epidemiology studies have shown statistical associations between ambient air
particulate matter (PM) concentrations and mortality/morbidity, particularly among …

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

N Li, T Xia, AE Nel - Free radical biology and medicine, 2008 - Elsevier
Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview

P Thangavel, D Park, YC Lee - International journal of environmental …, 2022 - mdpi.com
Several epidemiologic and toxicological studies have commonly viewed ambient fine
particulate matter (PM2. 5), defined as particles having an aerodynamic diameter of less …

[HTML][HTML] The effect of exposure time and concentration of airborne PM2. 5 on lung injury in mice: A transcriptome analysis

H Wang, X Shen, J Liu, C Wu, J Gao, Z Zhang, F Zhang… - Redox biology, 2019 - Elsevier
The association between airborne fine particulate matter (PM 2.5) concentration and the risk
of respiratory diseases has been well documented by epidemiological studies. However, the …