Atomic force microscopy in the study of macromolecular interactions in hemostasis and thrombosis: utility for investigation of the antiphospholipid syndrome

WJ Montigny, AS Quinn, XX Wu… - … in biology and …, 2006 - Wiley Online Library
This chapter demonstrates the unmatched efficacy of atomic force microscopy (AFM) for the
investigation of interactions occurring between biological cell-surface macromolecules on …

Atomic force microscopy: high resolution dynamic imaging of cellular and molecular structure in health and disease

DJ Taatjes, AS Quinn, JH Rand… - Journal of cellular …, 2013 - Wiley Online Library
The atomic force microscope (AFM), invented in 1986, and a member of the scanning probe
family of microscopes, offers the unprecedented ability to image biological samples unfixed …

Molecular views and measurements of hemostatic processes using atomic force microscopy

RE Marchant, I Kang, PS Sit, Y Zhou… - Current Protein and …, 2002 - ingentaconnect.com
Hemostasis and thrombosis are highly complex and coordinated interfacial responses to
vascular injury. In recent years, atomic force microscopy (AFM) has proven to be a very …

Biological applications of atomic force microscopy

R Lal, SA John - American Journal of Physiology-Cell …, 1994 - journals.physiology.org
The newly developed atomic force microscope (AFM) provides a unique window to the
microworld of cells, subcellular structures, and biomolecules. The AFM can image the three …

Use of atomic force microscopy for characterization of model membranes and cells

A Sadžak, L Mandić, S Šegota, V Strasser - Periodicum biologorum, 2023 - hrcak.srce.hr
Background: To provide a fundamental understanding of the potential and use of atomic
force microscopy (AFM) in medicine and the life sciences, this work presents a thorough …

The power of atomic force

H Feng - nature structural biology, 2000 - nature.com
Atomic force microscopy has an advantage over other microscope techniques in that
samples can be imaged under water or in aqueous buffer solutions. Thus, the structural …

Atomic force microscopy: seeing molecules of lipid and immunoglobulin

HG Hansma, AL Weisenhorn, AB Edmundson… - Clinical …, 1991 - academic.oup.com
The atomic force microscope (AFM) can image individual molecules by raster-scanning a
sharp tip over a surface. In this paper we present molecular-resolution images of …

Probing nanometer structures with atomic force microscopy

Z Shao - Physiology, 1999 - journals.physiology.org
Atomic force microscopy (AFM) can generate high-resolution images of the surface of
biological specimens and can also probe the interactions between and within single …

Toward mechanical manipulations of cell membranes and membrane proteins using an atomic force microscope: an invited review

A Ikai, R Afrin - Cell biochemistry and biophysics, 2003 - Springer
Recent advances in the use of the atomic force microscope (AFM) for manipulating cell
membranes and membrane proteins are reviewed. Early pioneering work on measurements …

Perspectives on over twenty years of life science research with atomic force microscopy and a look toward the future

B Ohler - Microscopy and Microanalysis, 2010 - cambridge.org
The potential for scanning probe microscopy to address topics in the life sciences was
recognized even in very early work by scanning tunneling microscope (STM) inventors …