Silicosis is the most common pneumoconiosis globally, with higher prevalence and
incidence in developing countries. To date, there is no effective treatment to halt or reverse …

Inhalation of silica particles is an environmental and occupational cause of silicosis, a type
of pneumoconiosis. Development of the lung silicosis is a unique process in which the …

Silicosis, an occupational lung disease that can be prevented, is still a significant public
health concern in many countries, despite its considerably decreased incidence over the …

Silicosis, characterized by irreversible pulmonary fibrosis, remains a major global public
health problem. Nowadays, cumulative studies are focusing on elucidating the pathogenesis …

As a fatal occupational disease with limited therapeutic options, molecular mechanisms
underpinning silicosis are still undefined. Herein, single-cell RNA sequencing of the lung …

Silicosis is a well‑known occupational disease, characterized by epithelial injury, fibroblast
proliferation, expansion of the lung matrix and dyspnea. At present, no effective treatment …

Silicosis is pneumoconiosis of the lung, usually resulting from prolonged exposure to
crystalline silica (CS). The hallmark of silicosis is excessive extracellular matrix (ECM) …

We hypothesized that infusion of bone marrow mononuclear cells (BMMCs) in the late
stages of silica-induced damage would reduce the remodelling process in a murine model …

Silicosis is caused by massive inhalation of silica-based particles, which leads to pulmonary
inflammation, pulmonary fibrosis and lung dysfunction. Currently, the pathophysiological …

Silicosis is a devastating occupational disease caused by long‐term inhalation of silica
particles, inducing irreversible lung damage and affecting lung function, without effective …