To evaluate whether there are age-related differences in the plasma concentration-vs-time
course of fentanyl, the authors administered fentanyl to seven infants (3–10 months), seven …

To determine whether the clearance of fentanyl in neonates varies with age, the authors
determined the pharmacokinetics of fentanyl in 14 humans ages 1-71 days and 15 lambs …

The pharmacokinetics of fentanyl were studied in fourteen neonates undergoing major
surgical procedures. Five patients were less than 1 day of age, seven ruere 1-4 days old …

The pharmacokinetics of fentanyl (F) were studied in 10 children, age 5 months-4.5 yr (mean
19 months) undergoing cardiac surgery with cardiopulmonary bypass (CPBP). They suffered …

IMPLICATIONS: In this pilot study of 10 children undergoing general anesthesia, we found
pharmacokinetic variables and plasma concentrations with the IV formulation of fentanyl …

Tolerance to opioid-induced sedation has been reported in neonates sedated with fentanyl
by continuous infusion while undergoing extracorporeal membrane oxygenation. We …

Fentanyl is a synthetic opioid that is very important in anesthetic practice because of its
relatively short time to peak analgesic effect and the rapid termination of action after small …

Fentanyl is used as an analgesic in small doses (1-2 micrograms X kg-1) and as an
anesthetic in very large doses (greater than 150 micrograms X kg-1). It has been …

Although fentanyl administration by continuous infusion in newborns during ventilatory
support has increased, pharmacokinetic data are lacking. Our objective was to determine …

The pharmacokinetics of transdermal fentanyl were assessed in eight children aged 18–60
months, weighing 11–20 kg and monitored postoperatively in the intensive care unit. A …