Osteoarthritis (OA) is one of the most common forms of degenerative joint disease and a
major cause of pain and disability affecting the aging population. It is estimated that more …

Osteoarthritis (OA) is a prevalent and disabling condition for which few safe and effective
therapeutic options are available. Current approaches are largely palliative and in an effort …

Osteoarthritis (OA) is the leading cause of function loss and disability among the elderly, with
significant burden on the individual and society. It is a severe disease for its high disability …

Osteoarthritis (OA) is a disease of the joints that affects several million individuals worldwide.
This disease, which involves mainly the diarthrodial joints, is chronic and develops slowly …

Osteoarthritis (OA) is a chronic painful arthritis with increasing global prevalence. Current
management involves non-pharmacological interventions and commonly used …

OBJECTIVE: The purpose of this article is to review the current status of drug development
as it relates to both molecular targets and clinical trials for osteoarthritis (OA). METHODS: A …

The prevalence of osteoarthritis (OA) and the burden associated with the disease are
steadily increasing worldwide, representing a major public health challenge for the coming …

Osteoarthritis (OA) is the most common form of arthritis, yet has historically lagged far behind
rheumatoid arthritis in terms of drug development. Despite the many challenges presented …

Introduction: Osteoarthritis (OA) is a leading cause of pain and disability among adults with a
current prevalence of around 15% and a predicted prevalence of 35% in 2030 for …

Osteoarthritis (OA) is a prevalent and severely debilitating disease with an unmet medical
need. In order to alleviate OA symptoms or prevent structural progression of OA, new drugs …