Overwhelming evidence exists that lifelong exercise is associated with a longer health span,
delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is the …

Regular exercise is a formidable regulator of insulin sensitivity and overall systemic
metabolism through both acute events driven by each exercise bout and through chronic …

Physical inactivity is one of the leading health problems in the world. Strong epidemiological
and clinical evidence demonstrates that exercise decreases the risk of more than 35 …

Exercise has long been known for its active role in improving physical fitness and sustaining
health. Regular moderate-intensity exercise improves all aspects of human health and is …

Obesity is a complex disease that affects whole body metabolism and is associated with an
increased risk of cardiovascular disease (CVD) and Type 2 diabetes (T2D). Physical …

Exercise may be described as a polypill to prevent and/or treat almost every chronic
disease, with obvious benefits such as its low cost and practical lack of adverse effects …

Currently, modern chronic diseases, including cardiovascular diseases, Type 2 diabetes,
metabolic syndrome, and cancer, are the leading killers in Westernized society and are …

In this review, we develop a blueprint for exercise biology research in the new millennium.
The first part of our plan provides statistics to support the contention that there has been an …

Highlights•Exercise is a powerful means to maintain health and prevent disease.•Exercise
increases energy expenditure and substrate utilization.•Acute and chronic exercise …

Although regular physical activity can prevent or reduce the risk of many age-related
diseases, the molecular mechanisms underpinning the protective effects of exercise are …