[HTML][HTML] Hyperpolarized 129Xe MR Imaging of Alveolar Gas Uptake in Humans
ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls… - PloS one, 2010 - journals.plos.org
Background One of the central physiological functions of the lungs is to transfer inhaled
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
Hyperpolarized 129Xe MRI of the human lung
JP Mugler III, TA Altes - Journal of Magnetic Resonance …, 2013 - Wiley Online Library
By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
Using hyperpolarized 129Xe gas-exchange MRI to model the regional airspace, membrane, and capillary contributions to diffusing capacity
Hyperpolarized 129Xe MRI has emerged as a novel means to evaluate pulmonary function
via 3D mapping of ventilation, interstitial barrier uptake, and RBC transfer. However, the …
via 3D mapping of ventilation, interstitial barrier uptake, and RBC transfer. However, the …
Translational applications of hyperpolarized 3He and 129Xe
Clinical magnetic resonance imaging of the lung is technologically challenging, yet over the
past two decades hyperpolarized noble gas (3He and 129Xe) imaging has demonstrated …
past two decades hyperpolarized noble gas (3He and 129Xe) imaging has demonstrated …
Accelerated interleaved spiral‐IDEAL imaging of hyperpolarized 129Xe for parametric gas exchange mapping in humans
Purpose To demonstrate the feasibility of mapping gas exchange with single breath‐hold
hyperpolarized (HP) 129Xe in humans, acquiring parametric maps of lung physiology. The …
hyperpolarized (HP) 129Xe in humans, acquiring parametric maps of lung physiology. The …
Hyperpolarized 129Xe MRI: a viable functional lung imaging modality?
S Patz, FW Hersman, I Muradian, MI Hrovat… - European journal of …, 2007 - Elsevier
The majority of researchers investigating hyperpolarized gas MRI as a candidate functional
lung imaging modality have used 3He as their imaging agent of choice rather than 129Xe …
lung imaging modality have used 3He as their imaging agent of choice rather than 129Xe …
Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …
PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …
terminal airway morphology rapidly and safely, providing novel information not possible …
Repeatability of regional pulmonary functional metrics of Hyperpolarized 129Xe dissolved‐phase MRI
AD Hahn, J Kammerman, M Evans… - Journal of Magnetic …, 2019 - Wiley Online Library
Background MRI of hyperpolarized 129Xenon (HP 129Xe) is increasingly utilized for
investigating pulmonary function. The solubility of HP 129Xe in lung tissue, blood plasma …
investigating pulmonary function. The solubility of HP 129Xe in lung tissue, blood plasma …
Imaging alveolar–capillary gas transfer using hyperpolarized 129Xe MRI
B Driehuys, GP Cofer, J Pollaro… - Proceedings of the …, 2006 - National Acad Sciences
Effective pulmonary gas exchange relies on the free diffusion of gases across the thin tissue
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …
Simultaneous magnetic resonance imaging of ventilation distribution and gas uptake in the human lung using hyperpolarized xenon-129
JP Mugler III, TA Altes, IC Ruset… - Proceedings of the …, 2010 - National Acad Sciences
Despite a myriad of technical advances in medical imaging, as well as the growing need to
address the global impact of pulmonary diseases, such as asthma and chronic obstructive …
address the global impact of pulmonary diseases, such as asthma and chronic obstructive …