Enarodustat: first approval

A Markham - Drugs, 2021 - Springer
The orally active hypoxia inducible factor-proly hydroxylase (HIF-PH) inhibitor enarodustat
(ENAROY®, Japan Tobacco) is being developed as an alternative to injectable …

Drugs activating hypoxia-inducible factors correct erythropoiesis and hepcidin levels via renal EPO induction in mice

T Nakai, Y Iwamura, K Kato, I Hirano… - Blood …, 2023 - ashpublications.org
The erythroid growth factor erythropoietin (EPO) is mainly produced by the kidneys in adult
mammals and induces expansion of erythroid cells and iron use for hemoglobin synthesis …