This paper presents an update from the Late Effects Study Group on 292 cases of second
malignant neoplasms (SMN) occurring in individuals who were diagnosed with their first …

A search of the records of 10 pediatric oncology centers revealed 102 children with more
than one malignant neoplasm. In this group of 102 patients, all pediatric cancers were seen …

Many pediatric and adolescent cancer patients are treated with carcinogenic
chemotherapeutic agents and radiation therapy to achieve permanent control of their …

The variation in the risk of solid second malignant neoplasms (SMN) with time since first
cancer during childhood has been previously reported. However, no study has been …

Of a cohort of 634 children treated from 1942 to 1969 at the Gustave Roussy Institute for a
first cancer and alive 5 years after treatment, 32 later developed second malignant …

As the cure rate for childhood malignancies increases, the number of patients at risk for
development of second malignancies also increases. Due to the potentially long remaining …

Studies were made of the development of second malignant tumors in children treated at the
Sidney Farber Cancer Institute. In 1973 a retrospective analysis identified second cancers in …

During the past several decades, remarkable advances have been achieved in the
treatment and survival of children with cancer. With the increasing population of childhood …

Background: Because survival rates among childhood cancer patients are increasing,
assessing the risk of second and subsequent malignant neoplasms (SMNs) is ever more …

The incidence of second malignant neoplasms (SMNs) in children was estimated from data
provided by ten paediatric oncology centres. During 1950-70 nearly 15 000 new patients …