Background The endothelial glycocalyx is a vasoprotective barrier between the blood and
endothelium. We hypothesized that glycocalyx degradation is present in preeclampsia, a …

We investigated whether disturbance of glycocalyx integrity is related with increased
cardiovascular risk. In 600 healthy subjects, we measured perfused boundary region (PBR) …

Severe inflammation has been shown to induce a shedding of the endothelial glycocalyx
(EGX). Inflammatory cytokines, such as tumor necrosis factor α (TNF-α), impede the …

Today pre-eclampsia (PE) is considered as a disease of various theories; still all of them
agree that endothelial dysfunction is the leading pathogenic factor. Endothelial dysfunction …

Damage to the endothelial glycocalyx, which helps maintain vascular homeostasis,
heightens the sensitivity of the vasculature to atherogenic stimuli. Patients with renal failure …

All human cells are coated by a surface layer of proteoglycans, glycosaminoglycans (GAGs)
and plasma proteins, called the glycocalyx. The glycocalyx transmits shear stress to the …

The endothelial glycocalyx exerts a wide array of vasculoprotective effects via inhibition of
coagulation and leucocyte adhesion, by contributing to the vascular permeability barrier and …

Chronic hyperglycemia underlies microvascular complications in patients with type 1
diabetes. The mechanisms leading to these vascular complications are not fully understood …

The endothelial glycocalyx (EG) as part of the endothelial surface layer (ESL) is an important
regulator of vascular function and homeostasis, including permeability, vascular tone …

Changes in endothelial glycocalyx are one of the earliest changes in development of
cardiovascular disease. The endothelial glycocalyx is both an important biological modifier …