NF-κB as a therapeutic target in chronic inflammation: recent advances
SS Makarov - Molecular medicine today, 2000 - cell.com
The family of nuclear factor κB (NF-κB) transcription factors is a topic of intense interest in the
biomedical community stemming from the role NF-κB plays in almost every aspect of cell …
biomedical community stemming from the role NF-κB plays in almost every aspect of cell …
NF-κB signaling in inflammation
The transcription factor NF-κB regulates multiple aspects of innate and adaptive immune
functions and serves as a pivotal mediator of inflammatory responses. NF-κB induces the …
functions and serves as a pivotal mediator of inflammatory responses. NF-κB induces the …
Roles of NF-κB in health and disease: mechanisms and therapeutic potential
ET Wong, V Tergaonkar - Clinical science, 2009 - portlandpress.com
The NF-κB (nuclear factor κB) family of transcription factors are involved in a myriad of
activities, including the regulation of immune responses, maturation of immune cells …
activities, including the regulation of immune responses, maturation of immune cells …
Nuclear factor-κB: its role in health and disease
A Kumar, Y Takada, AM Boriek… - Journal of molecular …, 2004 - Springer
Nuclear factor-κB (NF-κB) is a major transcription factor that plays an essential role in
several aspects of human health including the development of innate and adaptive …
several aspects of human health including the development of innate and adaptive …
NF-κB and the transcriptional control of inflammation
JP Mitchell, RJ Carmody - International review of cell and molecular …, 2018 - Elsevier
The NF-κB transcription factor was discovered 30 years ago and has since emerged as the
master regulator of inflammation and immune homeostasis. It achieves this status by means …
master regulator of inflammation and immune homeostasis. It achieves this status by means …
Transcription factor NF-κB: an update on intervention strategies
The nuclear factor (NF)-κB family of transcription factors are ubiquitous and pleiotropic
molecules that regulate the expression of more than 150 genes involved in a broad range of …
molecules that regulate the expression of more than 150 genes involved in a broad range of …
NF-κB regulation in the immune system
The nuclear factor-κB (NF-κB)/REL family of transcription factors has a central role in
coordinating the expression of a wide variety of genes that control immune responses. There …
coordinating the expression of a wide variety of genes that control immune responses. There …
NF-κB signaling and inflammation—Drug repurposing to treat inflammatory disorders?
A Roberti, LE Chaffey, DR Greaves - Biology, 2022 - mdpi.com
Simple Summary Since its first description 35 years ago, the transcription factor NF-κB
(nuclear factor κ-light-chain-enhancer of activated B cells) has been shown to be a key …
(nuclear factor κ-light-chain-enhancer of activated B cells) has been shown to be a key …
Nuclear factor kappa B—molecular biomedicine: the next generation
P Celec - Biomedicine & pharmacotherapy, 2004 - Elsevier
Nuclear factor kappa B (NFκB) as a transcription factor plays an important integrating role in
the intracellular regulation of immune response, inflammation and cell cycle regulation …
the intracellular regulation of immune response, inflammation and cell cycle regulation …
New insights into the role of nuclear factor-κB, a ubiquitous transcription factor in the initiation of diseases
F Chen, V Castranova, X Shi, LM Demers - Clinical chemistry, 1999 - academic.oup.com
Nuclear factor-κB (NF-κB) is a ubiquitous transcription factor that governs the expression of
genes encoding cytokines, chemokines, growth factors, cell adhesion molecules, and some …
genes encoding cytokines, chemokines, growth factors, cell adhesion molecules, and some …
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