GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer

S Christakoudi, E Evangelou, E Riboli, KK Tsilidis - Scientific reports, 2021 - nature.com
Genetic studies have examined body-shape measures adjusted for body mass index (BMI),
while allometric indices are additionally adjusted for height. We performed the first genome …

Visceral fat accumulation is associated with colorectal cancer in postmenopausal women

JY Lee, HS Lee, DC Lee, SH Chu, JY Jeon, NK Kim… - PloS one, 2014 - journals.plos.org
Background Obesity is a known risk factor for colorectal cancer (CRC), and emerging data
suggest that this association is mediated by visceral fat rather than total body fat. However …

Associations between obesity and changes in adult BMI over time and colon cancer risk

NL Nock, CL Thompson, TC Tucker, NA Berger, L Li - Obesity, 2008 - Wiley Online Library
Obesity has been associated with increased colon cancer risk in epidemiological studies;
however, the specific time periods during which obesity may be most relevant as well as …

Associations of body shape index (ABSI) and hip index with liver, metabolic, and inflammatory biomarkers in the UK Biobank cohort

S Christakoudi, E Riboli, E Evangelou, KK Tsilidis - Scientific Reports, 2022 - nature.com
Associations of liver, metabolic, and inflammatory biomarkers in blood with body shape are
unclear, because waist circumference (WC) and hip circumference (HC) are dependent on …

Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study

N Papadimitriou, CJ Bull, M Jenab, DJ Hughes, JA Bell… - BMC medicine, 2023 - Springer
Background Observational studies have linked childhood obesity with elevated risk of
colorectal cancer; however, it is unclear if this association is causal or independent from the …

Long‐term status of predicted body fat percentage, body mass index and other anthropometric factors with risk of colorectal carcinoma: two large prospective cohort …

A Hanyuda, DH Lee, S Ogino, K Wu… - … journal of cancer, 2020 - Wiley Online Library
Anthropometric measurements, such as body mass index (BMI), waist circumference, and
body fat percentage, have been used as indicators of obesity. Despite evidence that excess …

Risk and survival in colorectal cancer with increasing body mass index: A nationwide population‐based cohort study

U Saeed, TÅ Myklebust, TE Robsahm… - Colorectal …, 2023 - Wiley Online Library
Aim The aim was to explore potential associations between the body mass index (BMI) and
the risk of colorectal cancer (CRC), including subsites of the colon, and cancer‐specific …

Mendelian randomization study of body mass index and colorectal cancer risk

AP Thrift, J Gong, U Peters, J Chang-Claude… - … Biomarkers & Prevention, 2015 - AACR
Background: High body mass index (BMI) is consistently linked to increased risk of
colorectal cancer for men, whereas the association is less clear for women. As risk estimates …

Obesity, fat distribution and risk of cancer in women and men: a Mendelian randomisation study

NY Loh, W Wang, R Noordam, C Christodoulides - Nutrients, 2022 - mdpi.com
Obesity and upper-body fat distribution are independent, cardiometabolic risk factors but
whether they also display comparable associations with cancer risk is unknown. We …

A prospective study of body mass index, weight change, and risk of cancer in the proximal and distal colon

I Laake, I Thune, R Selmer, S Tretli, ML Slattery… - … , biomarkers & prevention, 2010 - AACR
Background: Body mass index (BMI) is an established risk factor for colon cancer, but risks
may differ between genders and colon subsites. Moreover, whether weight change …