Mouse-Adapted SARS-CoV-2 MA10 Strain Displays Differential Pulmonary Tropism and Accelerated Viral Replication, Neurodissemination, and Pulmonary Host …
CJ Thieulent, W Dittmar, UBR Balasuriya… - Msphere, 2023 - Am Soc Microbiol
Several models were developed to study the pathogenicity of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) as well as the in vivo efficacy of vaccines and …
syndrome coronavirus 2 (SARS-CoV-2) as well as the in vivo efficacy of vaccines and …
Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice
As of June, 2020, more than ten million cases of COVID-19 have been reported worldwide.
The causative pathogen of the disease is a novel coronavirus named severe acute …
The causative pathogen of the disease is a novel coronavirus named severe acute …
Comparison of the pathogenesis of SARS-CoV-2 infection in K18-hACE2 mouse and Syrian golden hamster models
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of
COVID-19, causes life-threatening disease. This novel coronavirus enters host cells via the …
COVID-19, causes life-threatening disease. This novel coronavirus enters host cells via the …
K18-hACE2 mice develop respiratory disease resembling severe COVID-19
SARS-CoV-2 emerged in late 2019 and resulted in the ongoing COVID-19 pandemic.
Several animal models have been rapidly developed that recapitulate the asymptomatic to …
Several animal models have been rapidly developed that recapitulate the asymptomatic to …
Characterization of two heterogeneous lethal mouse-adapted SARS-CoV-2 variants recapitulating representative aspects of human COVID-19
F Yan, E Li, T Wang, Y Li, J Liu, W Wang, T Qin… - Frontiers in …, 2022 - frontiersin.org
New emerging severe acute respiratory syndrome 2 (SARS-CoV-2) has caused a worldwide
pandemic. Several animal models of coronavirus disease 2019 (COVID-19) have been …
pandemic. Several animal models of coronavirus disease 2019 (COVID-19) have been …
SARS-CoV-2 causes lung infection without severe disease in human ACE2 knock-in mice
The development of mouse models for coronavirus disease 2019 (COVID-19) has enabled
testing of vaccines and therapeutics and defining aspects of severe acute respiratory …
testing of vaccines and therapeutics and defining aspects of severe acute respiratory …
Mouse models of lung-specific SARS-CoV-2 infection with moderate pathological traits
SH Kim, J Kim, JY Jang, H Noh, J Park… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus
disease 2019 (COVID-19) has been a global health concern since 2019. The viral spike …
disease 2019 (COVID-19) has been a global health concern since 2019. The viral spike …
Infection of wild-type mice by SARS-CoV-2 B. 1.351 variant indicates a possible novel cross-species transmission route
T Pan, R Chen, X He, Y Yuan, X Deng, R Li… - Signal transduction and …, 2021 - nature.com
COVID-19 is identified as a zoonotic disease caused by SARS-CoV-2, which also can cross-
transmit to many animals but not mice. Genetic modifications of SARS-CoV-2 or mice enable …
transmit to many animals but not mice. Genetic modifications of SARS-CoV-2 or mice enable …
Comparison of model‐specific histopathology in mouse models of COVID‐19
S Yang, L Cao, W Xu, T Xu, B Zheng, Y Ji… - Journal of medical …, 2022 - Wiley Online Library
A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has
been identified as the causative agent of the current coronavirus disease 2019 pandemic …
been identified as the causative agent of the current coronavirus disease 2019 pandemic …
SARS-CoV-2 variants of concern infect the respiratory tract and induce inflammatory response in wild-type laboratory mice
The emergence of new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
variants of concern pose a major threat to public health, due to possible enhanced virulence …
variants of concern pose a major threat to public health, due to possible enhanced virulence …
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