Purpose Diabetes mellitus (DM) is a metabolic disorder characterized by insulin deficiency
or insulin resistance. Pregabalin (PGB) is an antiepileptic drug with proven efficacy in the …

Objectives: Pregabalin (PGB) is used in drug-resistant epilepsy. Also, it has analgesic effects
in painful syndromes. Depression and anxiety are commonly seen in epilepsy and …

Abstract Anxiety Disorders and Posttraumatic Stress Disorders (PTSD) associated with type-
1 diabetes mellitus (T1DM) are increasingly common comorbidities and the treatment is …

Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to defects in
insulin secretion or its action. Complications from long-term diabetes consist of numerous …

Streptozotocin (STZ) induced neurotoxicity causes development of diabetic neuropathy in
rodent models and oxidative stress is the main culprit in development of diabetic …

Diabetes can exacerbate seizures and worsen seizure-related brain damage. In the present
study, we aimed to determine whether the standard antiepileptic drug pregabalin (PGB) …

Objective: The aim of this research was to evaluate analgesic, antioxidant, metabolic, and
cytotoxic effects of pregabalin (PGB), which is widely applied for the treatment of neuropathic …

Aim: To investigate the effect of gabapentin on neural [neuron-specific enolase (NSE)] and
glial markers [glial fibrillary acidic protein (GFAP) and S100B] in different brain regions of …

Introduction With the development of new neuroimaging tools it has become possible to
assess neurochemical alterations in patients experiencing chronic pain and to determine …

Background: Pregabalin (PGB) used as analgesic in remedy of neurogenic pains of
persistent diseases, is taken into consideration as one of the maximum abused anti-epileptic …