Humoral and T-cell response to SARS-CoV-2 vaccination in patients with multiple sclerosis treated with ocrelizumab

L Brill, A Rechtman, O Zveik, N Haham… - JAMA …, 2021 - jamanetwork.com
Importance B-cell–depleting therapies may affect the development of a protective immune
response following vaccination. Understanding the ability to develop vaccine-specific …

Omicron-specific cytotoxic T-cell responses after a third dose of mRNA COVID-19 vaccine among patients with multiple sclerosis treated with ocrelizumab

N Madelon, N Heikkilä, IS Royo, P Fontannaz… - JAMA …, 2022 - jamanetwork.com
Importance The SARS-CoV-2 variant B. 1.1. 529 (Omicron) escapes neutralizing antibodies
elicited after COVID-19 vaccination, while T-cell responses might be better conserved. It is …

Immunogenicity and safety of a third SARS-CoV-2 vaccine dose in patients with multiple sclerosis and weak immune response after COVID-19 vaccination

M König, HM Torgauten, T Holmøy, JT Vaage… - JAMA …, 2022 - jamanetwork.com
Methods| Patients from 3 university hospitals who were enrolled beginning on March 23,
2021, in an ongoing observational cohort study on immune responses after 2 doses of …

Association of disease-modifying treatment and anti-CD20 infusion timing with humoral response to 2 SARS-CoV-2 vaccines in patients with multiple sclerosis

G Disanto, R Sacco, E Bernasconi, G Martinetti… - JAMA …, 2021 - jamanetwork.com
Methods| We performed a prospective observational cohort study at the Neurocenter of
Southern Switzerland. Inclusion criteria were a diagnosis of MS (using the 2017 McDonald …

COVID‐19 vaccine response in people with multiple sclerosis

EC Tallantyre, N Vickaryous, V Anderson… - Annals of …, 2022 - Wiley Online Library
Objective The purpose of this study was to investigate the effect of disease modifying
therapies on immune response to severe acute respiratory syndrome‐coronavirus 2 (SARS …

Humoral immune response to COVID-19 mRNA vaccine in patients with multiple sclerosis treated with high-efficacy disease-modifying therapies

A Achiron, M Mandel, S Dreyer-Alster… - Therapeutic …, 2021 - journals.sagepub.com
Background and Aims: The National Multiple Sclerosis Society and other expert
organizations recommended that all patients with multiple sclerosis (MS) should be …

Immune responses to SARS‐CoV‐2 vaccination in multiple sclerosis: a systematic review/meta‐analysis

GY Gombolay, M Dutt, W Tyor - Annals of Clinical and …, 2022 - Wiley Online Library
Abstract Introduction Responses to SARS‐CoV‐2 vaccination in patients with MS (pwMS)
varies by disease‐modifying therapies (DMTs). We perform a meta‐analysis and systematic …

Serological response to SARS-CoV-2 vaccination in multiple sclerosis patients treated with fingolimod or ocrelizumab: an initial real-life experience

S Guerrieri, S Lazzarin, C Zanetta, A Nozzolillo… - Journal of …, 2022 - Springer
Background Recent observations suggest a lack of humoral response after SARS-CoV-2
vaccination in multiple sclerosis (MS) patients treated with fingolimod or ocrelizumab …

Tixagevimab and Cilgavimab (Evusheld) boosts antibody levels to SARS-CoV-2 in patients with multiple sclerosis on b-cell depleters

WL Conte, L Golzarri-Arroyo - Multiple sclerosis and related disorders, 2022 - Elsevier
Background and objectives B-cell-depleting therapies may affect the development of a
protective immune response following vaccination against SARS-CoV-2. It is important to …

SARS-CoV-2 antibodies in adult patients with multiple sclerosis in the Amsterdam MS cohort

ZLE Van Kempen, EMM Strijbis, MMCT Al… - JAMA …, 2021 - jamanetwork.com
Methods| This is a prospective cohort study conducted at the MS Center Amsterdam in
Amsterdam, the Netherlands. On July 31, 2020, all adult patients with a current diagnosis of …