Despite near ubiquity, information regarding fluids consumption at a health care systems
level, and patient exposure at an individual level, is surprisingly limited in the medical …

Management of volume status is difficult in critically ill patients with renal failure. Volumetric
hemodynamic indices are increasingly being used to guide fluid therapy in the intensive …

Background Hemorrhage is commonly treated with intravenous infusion of crystalloids.
However, the dynamics of fluid shifts between body fluid spaces are not completely known …

Objective: Dynamic preload indicators like pulse pressure variation (PPV) and stroke volume
variation (SVV) are increasingly being used for optimizing cardiac preload since they have …

Most critically ill patients in intensive care units (ICU) require fluid administration for volume
expansion at some point during their hospital stay.(1) In most cases, initial volume …

Purpose The mean systemic filling pressure (Pms) plays a central role for our understanding
of the circulation. In a retrospective analysis of a clinical trial, we studied whether Pms …

Hypovolemia, resulting from blood or water loss, vasoplegia, or a capillary leak, is one of the
most common reasons for shock states in the critically ill. Consequently, fluid replacement …

Objectives The objective of this study is to describe the changes on microcirculation after a
fluid challenge and describe the relationship with the changes on Pmsf. Our hypothesis is …

Evaluation of fluid volume status in critically ill patients is important in medical and surgical
management. However, commonly monitored variables, including pulmonary artery wedge …

Objective To discuss the clinical significance of fluid management of severe patients
according to arterial pressure-based cardiac output (APCO) monitoring volume …