Microfluidic cell culture systems for drug research

MH Wu, SB Huang, GB Lee - Lab on a Chip, 2010 - pubs.rsc.org
In pharmaceutical research, an adequate cell-based assay scheme to efficiently screen and
to validate potential drug candidates in the initial stage of drug discovery is crucial. In order …

Stem cells in microfluidics

D van Noort, SM Ong, C Zhang, S Zhang… - Biotechnology …, 2009 - Wiley Online Library
With the introduction of microtechnology and microfluidic platforms for cell culture, stem cell
research can be put into a new context. Inside microfluidics, microenvironments can be more …

Microfluidic platforms for single-cell analysis

RN Zare, S Kim - Annual review of biomedical engineering, 2010 - annualreviews.org
Microfluidics, the study and control of the fluidic behavior in microstructures, has emerged as
an important enabling tool for single-cell chemical analysis. The complex procedures for …

Biology on a chip: microfabrication for studying the behavior of cultured cells

N Li, A Tourovskaia, A Folch - Critical Reviews™ in Biomedical …, 2003 - dl.begellhouse.com
The ability to culture cells in vitro has revolutionized hypothesis testing in basic cell and
molecular biology research and has become a standard methodology in drug screening and …

Stem cells in microfluidics

HW Wu, CC Lin, GB Lee - Biomicrofluidics, 2011 - pubs.aip.org
Microfluidic techniques have been recently developed for cell-based assays. In microfluidic
systems, the objective is for these microenvironments to mimic in vivo surroundings. With …

Pumps for microfluidic cell culture

CK Byun, K Abi‐Samra, YK Cho, S Takayama - Electrophoresis, 2014 - Wiley Online Library
In comparison to traditional in vitro cell culture in Petri dishes or well plates, cell culture in
microfluidic‐based devices enables better control over chemical and physical environments …

Recent developments of microfluidics as a tool for biotechnology and microbiology

O Scheler, W Postek, P Garstecki - Current opinion in biotechnology, 2019 - Elsevier
Highlights•Microfluidics is transforming traditional techniques in biotechnology.•Multi-step
experiments are automated on single device in parallel reactors.•Millions of parallel …

[图书][B] Microfluidics for biological applications

WC Tian, E Finehout - 2009 - books.google.com
Microfluidics for Biological Applications provides researchers and scientists in the
biotechnology, pharmaceutical, and life science industries with an introduction to the basics …

Microfluidic cell culture models for tissue engineering

NK Inamdar, JT Borenstein - Current opinion in biotechnology, 2011 - Elsevier
Microfluidic systems have emerged as revolutionary new platform technologies for a range
of applications, from consumer products such as inkjet printer cartridges to lab-on-a-chip …

Single-cell manipulation and analysis using microfluidic devices

GT Roman, Y Chen, P Viberg, AH Culbertson… - Analytical and …, 2007 - Springer
Cells are extremely complex and dynamic biochemical entities. Significant biochemical
heterogeneity can exist among cells of the same type. This heterogeneity may arise via …