We introduce the first lab-on-a-chip platform for complete mammalian cell culture. The new
method is powered by digital microfluidics (DMF), a technique in which nanolitre-sized …

This review covers several aspects of microfluidic devices used for culturing and monitoring
of both adherent and non-adherent cells, including a multitude of applications. A comparison …

Highlights•Microfluidics complements high sensitivity molecular tools, allowing single cell
analysis.•Cells can be directly manipulated by a variety of fields, with forces equivalent …

Culturing cells at microscales allows control over microenvironmental cues, such as cell–cell
and cell–matrix interactions; the potential to scale experiments; the use of small culture …

Stem cell research can significantly benefit from recent advances of microfluidics
technology. In a rationally designed microfluidic device, analyses of stem cells can be done …

Microfluidic cell-separation technologies have been studied for almost two decades, but the
limited throughput has restricted their impact and range of application. Recent advances in …

The basic concepts that underly the field of microfluidics started in 1990 from a vision of
integrating all chemical analysis processes onto a microfabricated chip. A decade later …

Single-cell analysis is essential to improve our understanding of cell functionality from
cellular and subcellular aspects for diagnosis and therapy. Single-cell cultivation is one of …

Microfluidic platforms are microfabricated tools that are gaining popularity for studying of
cellular biology. These platforms can allow precise control of the environment surrounding …

Analysis of the profiles and dynamics of molecular components and sub-cellular structures
in living cells using microfluidic devices has become a major branch of bioanalytical …