Serial Intravascular Ultrasound Assessment of Atherosclerosis Progression and Regression State-of-the-Art and Limitations

GS Mintz, A Maehara - Circulation Journal, 2009 - jstage.jst.go.jp
Coronary heart disease remains a leading cause of morbidity and mortality. Surrogate
imaging endpoints may allow smaller sample sizes and shorter study durations to expedite …

Intravascular ultrasound assessment of atherosclerosis

A Guédès, JC Tardif - Current atherosclerosis reports, 2004 - Springer
Atherosclerosis imaging has taken on increasing importance in the understanding of the
natural history of coronary artery disease and the processes leading to luminal narrowing …

Intravascular ultrasound imaging for assessing regression and progression in coronary artery disease

H Kaneda, J Ako, M Terashima - The American journal of cardiology, 2010 - Elsevier
New imaging techniques have been used as surrogate markers of atherosclerotic burden to
determine the effects of pharmacologic intervention. The aim of this study was to better …

Intravascular ultrasound for the evaluation of therapies targeting coronary atherosclerosis

D Böse, C von Birgelen, R Erbel - Journal of the American College of …, 2007 - jacc.org
Many cardiovascular events are clinical manifestations of underlying atherosclerotic
disease. The progression of atherosclerosis, traditionally measured by angiography, is …

Role of imaging end points in atherosclerosis trials: focus on intravascular ultrasound

SR Kalidindi, EM Tuzcu… - International journal of …, 2007 - Wiley Online Library
Increasing attention has been focused on the appropriate role of surrogate markers in the
development of novel anti‐atherosclerotic therapies. Technological advances in imaging …

Assessment of progression and regression of coronary atherosclerosis by intravascular ultrasound. A new paradigm shift?

SJ Nicholls, I Sipahi, EM Tuzcu - Revista Española de Cardiología (English …, 2006 - Elsevier
Intravascular ultrasound (IVUS) has emerged as a powerful imaging modality for the
assessment of the arterial wall and it's response to the accumulation of atherosclerotic …

The role of intravascular ultrasound in the determination of progression and regression of coronary artery disease

H Kaneda, M Terashima, H Yamaguchi - Current atherosclerosis reports, 2012 - Springer
New imaging techniques have been used to examine surrogate markers of atherosclerotic
burden to determine the effects of pharmacologic intervention. In this review, we discuss the …

Coronary intravascular ultrasound: implications for understanding the development and potential regression of atherosclerosis

AC De Franco, SE Nissen - The American journal of cardiology, 2001 - Elsevier
The incremental value of intravascular ultrasound (IVUS), compared with angiographic
analysis of coronary atherosclerosis, originates principally from 2 key features—its …

Coronary angiography and intravascular ultrasound

S Nissen - The American journal of cardiology, 2001 - Elsevier
Clinicians have long used the size of the lumen and the angiogram as a predictor of
coronary events. However, cardiovascular disease is not a disease of the lumen but a …

[PDF][PDF] Intravascular ultrasonography: using imaging end points in coronary atherosclerosis trials

P Schoenhagen, SE Nissen - Cleveland Clinic journal of medicine, 2005 - cdn.mdedge.com
■ ABSTRACT Intravascular ultrasonography (IVUS) can precisely measure plaque burden
and is being used to test new drug therapies. Other imaging tests may also prove useful to …