The malignancy of non–small cell lung cancer (NSCLC) largely results from its invasive
manner. Secreted frizzled-related proteins (SFRPs) have been recently found to suppress …

Colorectal cancer (CRC) is one of the main causes of death in the world. Diagnosis in
precancerous lesions stage is an important factor in reducing the mortality rate in CRC. Our …

Background Secreted frizzled-related protein 2 (SFRP2) in circulating tumor DNA (ctDNA) is
related to gastric cancer (GC) proliferation. However, whether methylated SFRP2 in ctDNA …

METHODS sFRP-5 expression levels were examined in 22 normal and 24 cancer regions of
clinical samples using tissue microarray. sFRP-5 mRNA expression was also checked by …

Glioblastoma multiforme (GBM) are intracranial tumors of the central nervous system and the
most lethal among solid tumors. Current therapy is palliative and is limited to surgical …

Background Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRPs family
that modulates the Wnt signal transduction pathway. Recent studies have showed down …

Objective To investigate the expressions of secreted frizzled-related protein 4 (SFRP4) in
stage Ⅱ DNA mismatch repair-deficient (dMMR) and mismatch repair-proficient (pMMR) …

Purpose Secreted frizzled related proteins (SFRPs) play important roles in tumor progress
through antagonizing Wnt signaling. However, SFRPs has not been systematically studied …

Background/Aims: Choriocarcinoma (CC) is a highly aggressive gestational trophoblastic
neoplasia; however, the underlying molecular mechanisms of its invasiveness and …

Background Secreted frizzled-related protein 1 (sFRP1), Wnt signalling regulator, can
positively or negatively regulate tumourigenesis and progression. We sought to determine …