Liver fibrosis occurs in response to chronic liver injury and is characterized by an excessive
deposition of extracellular matrix. Activated hepatic stellate cells are primarily responsible for …

Mesenchymal stromal cells (MSCs) are considered as a promising therapeutic tool for liver
fibrosis, a main feature of chronic liver disease. Because small extracellular vesicles (sEVs) …

Extracellular vesicles (EVs) are nano-sized membrane-limited organelles that are liberated
from their producer cells, traverse the intercellular space, and may interact with other cells …

Allogeneic transplantation of mesenchymal stem cell-derived extracellular vesicles (EVs)
offers great potential for treating liver fibrosis. However, owing to their intrinsic surface …

Background Extracellular vesicles derived from mesenchymal stem/stromal cells (MSCs)
have shown therapeutic effects on liver fibrosis. This study aimed to evaluate the effects of …

Hepatic fibrosis (HF) is involved in aggravated wound‐healing response as chronic liver
injury. Extracellular vesicles (EVs) carrying microRNA (miR) have been reported as …

Abstract Background: The extracellular vesicles (EVs) secreted by bone marrow-derived
mesenchymal stem cells (MSCs) hold significant potential as a novel alternative to whole …

End-stage liver fibrosis is common to all chronic liver diseases. Since liver transplantation
has several limitations, including lack of donors, immunological rejection, and high medical …

Progression of fibrosis and the development of cirrhosis are responsible for the liver-related
morbidity and mortality associated with chronic liver diseases. There is currently a great …

Liver fibrosis (LF) is a major cause of morbidity and mortality worldwide. Hepatic stellate
cells (HSCs) are the primary source of extracellular matrix in the liver and their activation is a …