Human liver stem cell derived extracellular vesicles alleviate kidney fibrosis by interfering with the β-catenin pathway through miR29b
S Kholia, MB Herrera Sanchez, MC Deregibus… - International Journal of …, 2021 - mdpi.com
Human liver stem-cell-derived extracellular vesicles (HLSC-EVs) exhibit therapeutic
properties in various pre-clinical models of kidney injury. We previously reported an overall …
properties in various pre-clinical models of kidney injury. We previously reported an overall …
[PDF][PDF] The niche of stellate cells within rat liver
I Sawitza, C Kordes, S Reister, D Häussinger - Hepatology, 2009 - Wiley Online Library
It is well‐accepted that hepatic stellate cells (HSCs) can develop into myofibroblast‐like cells
that synthesize extracellular matrix proteins and contribute to liver fibrosis. Recently …
that synthesize extracellular matrix proteins and contribute to liver fibrosis. Recently …
[HTML][HTML] Unraveling the emerging niche role of hepatic stellate cell-derived exosomes in liver diseases
KL Yin, M Li, PP Song, YX Duan, WT Ye… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Hepatic stellate cells (HSCs) play an essential role in various liver diseases, and exosomes
are critical mediators of intercellular communication in local and distant microenvironments …
are critical mediators of intercellular communication in local and distant microenvironments …
Extracellular vesicles derived from human liver stem cells attenuate chronic kidney disease development in an in vivo experimental model of renal ischemia and …
S Bruno, G Chiabotto, M Cedrino, E Ceccotti… - International Journal of …, 2022 - mdpi.com
The potential therapeutic effect of extracellular vesicles (EVs) that are derived from human
liver stem cells (HLSCs) has been tested in an in vivo model of renal ischemia and …
liver stem cells (HLSCs) has been tested in an in vivo model of renal ischemia and …
Human mesenchymal stromal cell-derived extracellular vesicles improve liver regeneration after ischemia reperfusion injury in mice
F Anger, M Camara, E Ellinger, CT Germer… - Stem Cells and …, 2019 - liebertpub.com
Hepatic ischemia reperfusion injury (IRI) remains a major obstacle in liver resection and
transplantation surgery, especially in diseased organs. Human mesenchymal stromal cells …
transplantation surgery, especially in diseased organs. Human mesenchymal stromal cells …
[HTML][HTML] Bone marrow stem cells anti-liver fibrosis potency: inhibition of hepatic stellate cells activity and extracellular matrix deposition
EJ Sitanggang, RD Antarianto… - … Journal of Stem Cells, 2017 - ncbi.nlm.nih.gov
Transplantation of bone marrow derived stem cells (BMSCs) has been reported inhibits liver
fibrosis. Several in vitro studies by co-culturing BMSCs and hepatic stellate cells (HSCs) …
fibrosis. Several in vitro studies by co-culturing BMSCs and hepatic stellate cells (HSCs) …
Extracellular vesicles derived from human embryonic stem cell‐MSCs ameliorate cirrhosis in thioacetamide‐induced chronic liver injury
S Mardpour, SN Hassani, S Mardpour… - Journal of cellular …, 2018 - Wiley Online Library
Various somatic tissue‐derived mesenchymal stromal cells (MSCs) have been considered
as an attractive therapeutic tool for treatment of liver diseases in which the secretion of …
as an attractive therapeutic tool for treatment of liver diseases in which the secretion of …
Mesenchymal stem cells improve liver fibrosis and protect hepatocytes by promoting microRNA-148a-5p-mediated inhibition of Notch signaling pathway
Q Zhou, C Rong, T Gu, H Li, L Wu, X Zhuansun… - Stem Cell Research & …, 2022 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are considered to be a potential
therapeutic tool for liver fibrosis. Inhibiting the activation of hepatic stellate cells (HSCs) and …
therapeutic tool for liver fibrosis. Inhibiting the activation of hepatic stellate cells (HSCs) and …
Mesenchymal stem cell-derived extracellular vesicles in liver immunity and therapy
R Wu, X Fan, Y Wang, M Shen, Y Zheng… - Frontiers in …, 2022 - frontiersin.org
Mesenchymal stem cells (MSCs), as the most common cell source for stem cell therapy, play
an important role in the modulation of innate and adaptive immune responses and have …
an important role in the modulation of innate and adaptive immune responses and have …
[PDF][PDF] Incomplete differentiation of engrafted bone marrow endothelial progenitor cells initiates hepatic fibrosis in the rat
AC Maretti‐Mira, X Wang, L Wang, LD DeLeve - Hepatology, 2019 - Wiley Online Library
Normal liver sinusoidal endothelial cells (LSECs) promote quiescence of hepatic stellate
cells (HSCs). Prior to fibrosis, LSECs undergo capillarization, which is permissive for HSC …
cells (HSCs). Prior to fibrosis, LSECs undergo capillarization, which is permissive for HSC …