Gentamicin (GEN) is an antibiotic to treat severe gram-negative infections. Nephrotoxicity is
the major adverse effect limiting clinical use of GEN. Zingerone (ZIN), an important …

Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces renal
damage by overproduction of reactive oxygen species and inflammation in proximal tubular …

Ginger or Zingiber officinale which is used in traditional medicine has been found to possess
antioxidant effect that can control the generation of free radicals. Free radicals are the …

The current investigation was considered to evaluate the beneficial effects of gentisic acid
(GA) on gentamicin (GEN)-induced nephrotoxicity in rat kidneys through assessment of …

The effect of Ginkgo biloba (EGb), a plant extract with an antioxidant effect, has been studied
on gentamicin-induced nephrotoxicity in male wistar rats. Ginkgo biloba extract (300 mg/kg …

Background: Gentamicin (GM) is a commonly used aminoglycoside, however, renal toxicity
has limited its usage. This study was designed to evaluate the curative and protective effects …

The toxicity of aminoglycosides including gentamicin (GEN), the most widely used drug in
this category, is believed to be related to the generation of reactive oxygen species (ROS) in …

Background Gentamicin is an effective aminoglycoside antibiotic employed against severe
Gram-negative bacterial infections, but induction of nephrotoxicity limits its frequent clinical …

The major side effect of gentamicin (GEN) is nephrotoxicity which in turn restricts the clinical
use of this drug. In this study, the effect of gallic acid (GA) on gentamicin-induced …

Background: Gentamicin (GM) is the commonly used antibiotics against Gram-negative
infection, but the nephrotoxic potential of drug limit its clinical interest. The aim of this study …