Inv (16)(p13q22) and the related translocation t (16; 16)(p13; q22) generate a CBFB-MYH11
fusion gene transcript and are commonly found in acute myeloid leukemia (AML) M4Eo. 1 …

The inv (16)(p13q22) rearrangement is present in approximately 10% of cases with de novo
acute myeloid leukemia (AML) and results in a CBFB-MYH11 gene fusion. 1 Patients with …

The spectrum of CBFB-MYH11 fusion transcripts in acute myeloid leukemia (AML) M4eo
with inv (16)/t (16; 16) is heterogeneous. Approximately 85% show type A CBFB-MYH11 …

The cytogenetic findings in acute myeloid leukemia (AML) are a powerful prognostic
indicator. Among these abnormalities, the World Health Organization has classified inv …

Purpose To evaluate the prognostic impact of minimal residual disease (MRD) in patients
with acute myeloid leukemia (AML) expressing the CBFB-MYH11 fusion transcript. Patients …

Abstract Inv (16)(p13q22) and t (16; 16)(p13; q22) are cytogenetic hallmarks of acute
myelomonoblastic leukaemia, most of them associated with abnormal bone marrow …

It has been established that cytogenetic findings at diagnosis of acute myeloid leukaemia
(AML) are a powerful prognostic indicator. Patients who have the inv (16)(p13q22), closely …

Acute myeloid leukemia (AML) with the inv (16)/t (16; 16) karyotype is associated with a
favourable prognosis, showing longer periods of complete remission and high overall …

Acute myeloid leukemia (AML) carrying inv (16)/t (16; 16), resulting in fusion transcript CBFB-
MYH11, belongs to the favorable-risk category. However, even if most patients obtain …

Acute myeloid leukemia (AML) with an inv (16)(p13q22) or t (16; 16)(p13; q22) chromosomal
abnormality represents one of the most common subtypes of de novo cases. These …