We have previously described a negative feedback loop that inhibits duodenal motility when
nutrients are infused into the ileum and colon. In the present study, we examined the role of …

To explore mechanisms whereby unabsorbed nutrients in the ileum inhibit the upper gut ("
ileal brake"), we perfused the canine ileum or colon and monitored phase 3 in the …

The aims of this study were to determine the effects of duodenal and jejunoileal nutrient
infusions on small intestinal motor patterns and intestinal contractions in neurally intact and …

Little is known on the effects of enteral nutrition on intestinal motor patterns. In dogs,
intestinal motility was recorded with multiple extra‐luminal strain‐gauges. An elemental diet …

In the present study, effects of ileal infusions of nutrients on motor patterns of the proximal
small intestine and on gastric emptying were investigated in dogs. An acaloric meal was …

Ingestion of a meal converts the fasting motor pattern, the migrating motor complex (MMC),
to a fed pattern of motility. The role of specific anatomic gut regions involved in these …

Our aim was to determine the roles of extrinsic and intrinsic (enteric) neural continuity to the
jejunoileum in control of postprandial and fasting motility patterns. Four groups of dogs were …

The motility of the gut depends on the chemicals contained in the lumen, but the stimuli that
modify motility and their relationship to enteric neural pathways are unclear. This study …

Digestion and absorption of a meal are time-intensive processes. To optimize digestion and
absorption, transit of the meal through the gastrointestinal tract is regulated by a complex …

Our aim was to determine the mechanism whereby the jejunoileum regulates postprandial
gastroduodenal motility. Five dogs were prepared with a proximal jejunal infusion catheter …