Lack of association of angiotensin converting enzyme gene polymorphism or serum enzyme activity with coronary artery disease in Japanese subjects

T Fujimura, M Yokota, S Kato… - American journal of …, 1997 - academic.oup.com
The association of an insertion/deletion (I/D) polymorphism in the angiotensin converting
enzyme (ACE) gene or the serum activity of ACE with coronary artery disease (CAD) was …

Genetics of angiotensin I-converting enzyme

O Costerousse, S Danilov… - Clinical and experimental …, 1997 - Taylor & Francis
The ACE gene is constitutively expressed in several types of somatic cells, including
vascular cells. A soluble form of the enzyme is secreted in plasma by proteolytic cleavage of …

Increased urinary excretion of angiotensin converting enzyme in patients with renal diseases

I Kato, Y Takada, K Nishimura, K Hiwada, T Kokubu - 1982 - degruyter.com
We measured the activity of angiotensin converting enzyme (EC 3.4. 15.1) in urine samples
from normal subjects and patients with nephrotic syndrome and chronic glomerulonephritis …

Angiotensin-I converting enzyme

K Nakai, T Syoh, K Hiramori - Nihon rinsho. Japanese Journal of …, 1995 - europepmc.org
Angiotensin I-converting enzyme (ACE) converts the largely inactive decapeptide
angiotensin I to the active octapeptide angiotensin II. ACE is a key component of the renin …

Measurement of converting enzyme activity by antibody-trapping of generated angiotensin II: comparison with two other methods

J Nussberger, D Brunner, I Keller… - American journal of …, 1992 - academic.oup.com
Activity of the angiotensin converting enzyme (ACE) is usually measured in vitro by
estimation of products cleaved by the enzyme from synthetic substrates. These substrates …

Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion

RA Gonzalez-Villalobos, S Billet, C Kim… - Journal of the …, 2011 - journals.lww.com
The contribution of the intrarenal renin-angiotensin system to the development of
hypertension is incompletely understood. Here, we used targeted homologous …

Differential regulation of vascular angiotensin I-converting enzyme in hypertension.

MS Fernandez-Alfonso, R Kreutz, K Zeh, Y Liu… - …, 1994 - Am Heart Assoc
The angiotensin I-converting enzyme (ACE) gene is found on the locus that has been linked
to high blood pressure after sodium loading in rats, so in the present study we investigated …

Development of enzyme-linked immunoassays for human angiotensin I converting enzyme suitable for large-scale studies

S Danilov, F Savoie, B Lenoir… - Journal of …, 1996 - journals.lww.com
Objective: To develop and validate a simple immunological assay for human angiotensin
converting enzyme (ACE) based on monoclonal antibodies. Methods: Microtitre plates were …

Characterization of angiotensin converting enzyme from different rat vascular beds

K Jandeleit-Dahm, B Jackson, D Paxton, R Perich… - Blood …, 1995 - Taylor & Francis
The tissue renin angiotensin system may play a role in cardiovascular pathophysiology.
Angiotensin converting enzyme in tissues is now a target for pharmacological inhibition. It is …

Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin–I-converting enzyme deletion/deletion genotype

JE Jalil, C Palomera, MP Ocaranza, I Godoy… - The American journal of …, 2003 - Elsevier
In patients with hypertension who have the DD-ACE genotype (higher angiotensin-
converting enzyme [ACE] activity), plasma levels of angiotensin-(1-7) are 4 times lower than …