The association between circulating angiotensin-converting enzyme and cardiovascular risk in the elderly: a cross-sectional study

L Ljungberg, U Alehagen, T Länne… - Journal of the Renin …, 2011 - journals.sagepub.com
Introduction: A polymorphism in the angiotensin-converting enzyme gene (ACE I/D
polymorphism) has been associated with increased risk for cardiovascular disease (CVD) …

Blood pressure control by the renin-angiotensin system in normotensive subjects. Assessment by angiotensin converting enzyme and renin inhibition.

W Kiowski, L Linder, C Kleinbloesem… - Circulation, 1992 - Am Heart Assoc
BACKGROUND The participation of the renin-angiotensin system in the control of blood
pressure in normal, sodium-replete subjects is not clear. The use of a specific inhibitor of …

Angiotensin I-converting enzyme gene polymorphism and acute response to captopril in essential hypertension

Y Nakano, T Oshima, M Watanabe… - American journal of …, 1997 - academic.oup.com
Abstract Insertion/deletion (I/D) polymorphism of the angiotensin converting enzyme (ACE)
gene has been shown to be a determinant for serum ACE level and a marker for several …

What we would like to know about the antihypertensive mechanisms of angiotensin converting enzyme inhibition.

HR Brunner, B Waeber, J Nussberger - Journal of hypertension …, 1988 - europepmc.org
Angiotensin converting enzyme (ACE) inhibitors induce haemodynamic, humoral and
metabolic actions which have been well characterized during the last decade. The precise …

Angiotensin-converting enzyme 2 activity in patients with chronic kidney disease

MA Roberts, E Velkoska, FL Ierino… - Nephrology Dialysis …, 2013 - academic.oup.com
Background Angiotensin-converting enzyme 2 (ACE2) is a novel regulator of the renin–
angiotensin system that counteracts the adverse effects of angiotensin II. In heart failure …

Renin-angiotensin system in essential hypertension

M Aurell, M Pettersson, G Berglund - The Lancet, 1975 - Elsevier
In a random sample of normotensive and hypertensive fifty-year-old men plasma-renin-
activity (PRA), plasma-renin-concentration (PRC), and renin substrate were measured using …

Angiotensin‐converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor

RA Lew, FJ Warner, I Hanchapola… - Experimental …, 2008 - Wiley Online Library
Angiotensin‐converting enzyme 2 (ACE2) is thought to act in an opposing manner to its
homologue, angiotensin‐converting enzyme (ACE), by inactivating the vasoconstrictor …

The angiotensin converting enzyme in the kidney

F Alhenc-Gelas, T Baussant, C Hubert… - Journal of …, 1989 - journals.lww.com
Immunohistochemical studies and experiments with microdissected nephron segments
indicate that the angiotensin I converting enzyme (ACE) in the kidney is expressed in the …

[引用][C] Plasma renin and angiotensin levels in human hypertension following treatment

CI Johnston, N Anavekar, KG Chua… - Clinical Science and …, 1973 - portlandpress.com
1. The levels of plasma renin activity or concentration and plasma angiotensin were similar
in normotensive subjects and in untreated or treated essential hypertensives. 2. There was a …

Effect of reduced angiotensin-converting enzyme gene expression and angiotensin-converting enzyme inhibition on angiotensin and bradykinin peptide levels in mice

DJ Campbell, T Alexiou, HD Xiao, S Fuchs… - …, 2004 - Am Heart Assoc
There is uncertainty about the contribution of angiotensin-converting enzyme (ACE) to
angiotensin II formation, with recent studies suggesting that non-ACE enzymes may be the …